• 1. Vernau KM, Runstadler JA, Brown EA, et al. Genome-wide association analysis identifies a mutation in thiamine transporter 2 (SLC19A3) gene associated with Alaskan Husky encephalopathy. PLoS One 2013;8:e57195.

    • Search Google Scholar
    • Export Citation
  • 2. Brenner O, Wakshlag JJ, Summers BA, et al. Alaskan Husky encephalopathy—a canine neurodegenerative disorder resembling subacute necrotizing encephalomyelopathy (Leigh syndrome). Acta Neuropathol 2000;100:5062.

    • Search Google Scholar
    • Export Citation
  • 3. Wakshlag JJ, de Lahunta A, Robinson T, et al. Subacute necrotising encephalopathy in an Alaskan Husky. J Small Anim Pract 1999;40:585589.

    • Search Google Scholar
    • Export Citation
  • 4. Mellema LM, Koblik PD, Kortz GD, et al. Reversible magnetic resonance imaging abnormalities in dogs following seizures. Vet Radiol Ultrasound 1999;40:588595.

    • Search Google Scholar
    • Export Citation
  • 5. Wisner ER, Zwingenberger AL. Metabolic, toxic, and degenerative disorders. In: Wisner ER, Zwingenberger AL, eds. Atlas of small animal CT and MRI. Ames, Iowa: Wiley Blackwell, 2015;184196.

    • Search Google Scholar
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  • 1 1Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada.
History

A 13-month-old 21.6-kg (47.5-lb) castrated male Alaskan Husky mix was examined at the Western College of Veterinary Medicine because of seizures, blindness, and behavioral changes. The dog had had 4 generalized tonic-clonic seizures witnessed by the owner during the 7 days prior to the examination. The owners reported that 2 days after the first seizure, the dog seemed reluctant to descend stairs or jump, was ataxic, and bumped into objects. The dog had been adopted from the local humane society 10 months earlier, and there had been no previous health concerns. The dog did not have a history of

Contributor Notes

Dr. Zwueste's present address is Vancouver Animal Emergency and Referral Centre, 2303 Alberta St, Vancouver, BC V5Y 4A7, Canada.

Address correspondence to Dr. Zwueste (dmz5l4@mail.usask.ca).