Objective—To evaluate time to first recurrence (TFR)
and overall survival in cats with presumed vaccine-associated
sarcomas (VAS) treated with excision.
Animals—61 cats with presumed VAS.
Procedure—Medical records of cats that received
excision as the only initial treatment for presumed
VAS were reviewed to evaluate prognosis. Overall
survival curves and TFR were determined.
Results—Median TFR was 94 days. Median TFR for
tumors treated with excision performed at a referral
institution (274 days) was significantly longer than that
for tumors excised by a referring veterinarian (66 days).
Radical first excision yielded significantly longer median
TFR (325 days) than did marginal first excision (79
days). Cats with tumors located on the limbs had
longer median TFR (325 days) than cats with tumors
located in other sites (66 days). Median overall survival
time was 576 days. Significant differences in survival
times between groups were not detected. Few cats
(13.8%) receiving only surgical treatment had longterm
(> 2 years) survival.
Conclusions and Clinical Relevance—Radical first
excision of presumed VAS is essential for extended
TFR. Current recommendations for vaccination of the
distal portions of the extremities are appropriate,
because this practice permits radical excision of
tumors (amputation) that develop at vaccination sites;
however, surgery alone is seldom curative. ( J Am Vet
Med Assoc 2000;216:58–61)