• 1 de Groat WC, Griffiths D, Yoshimura N. Neural control of the lower urinary tract. Compr Physiol 2015;5:327396.

  • 2 Hu HZ, Granger N, Jeffrey ND. Pathophysiology, clinical importance, and management of neurologic lower urinary tract dysfunction caused by suprasacral spinal cord injury. J Vet Intern Med 2016;30:15751588.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 3 Bubenik L, Hosgood G. Urinary tract infection in dogs with thoracolumbar intervertebral disc herniation and urinary bladder dysfunction managed by manual expression, indwelling catheterization or intermittent catheterization. Vet Surg 2008;37:791800.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 4 Davis GJ, Brown DC. Prognostic indicators for time to ambulation after surgical decompression in nonambulatory dogs with acute thoracolumbar disk extrusions: 112 cases. Vet Surg 2002;31:513518.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5 Sterna J, Burzykowski T. The assessment of the usefulness of hemilaminectomy without fenestration in the treatment of thoracolumbar disc disease in chondrodystrophic dogs. Pol J Vet Sci 2007;10:165172.

    • Search Google Scholar
    • Export Citation
  • 6 Aikawa T, Fujita H, Kanazono S, et al. Long-term neurologic outcome of hemilaminectomy and disk fenestration for treatment of dogs with thoracolumbar intervertebral disk herniation: 831 cases (2000–2007). J Am Vet Med Assoc 2012;241:16171626.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7 Olby N, Harris T, Burr J, et al. Recovery of pelvic limb function in dogs following acute intervertebral disc herniation. J Neurotrauma 2004;21:4959.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 8 Rousse CA, Olby N, Williams K, et al. Recovery of stepping and coordination in dogs following acute thoracolumbar intervertebral disc herniation. Vet J 2016;213:5963.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9 Song RB, Basso DM, da Costa RC, et al. Adaption of the Basso-Beattie-Bresnahan locomotor rating scale for use in a clinical model of spinal cord injury in dogs. J Neurosci Methods 2016;268:117124.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10 Atalan G, Parkinson TJ, Barr FJ, et al. Urine volume estimations in dogs recovering from intervertebral disc prolapse surgery. Berl Munch Tierarztl Wochenschr 2002;115:303305.

    • Search Google Scholar
    • Export Citation
  • 11 Levine GJ, Levine JM, Budke CM, et al. Description and repeatability of a newly developed spinal cord injury scale for dogs. Prev Vet Med 2009;89:121127.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 12 Griffin JF IV, Levine J, Kerwin S. Canine thoracolumbar intervertebral disk disease: pathophysiology, neurologic examination, and emergency medical treatment. Compend Contin Educ Vet 2009;31:E2.

    • Search Google Scholar
    • Export Citation
  • 13 Levine JM, Cohe ND, Heller M, et al. Efficacy of a metalloproteinase inhibitor in spinal cord injured dogs. PLoS One 2014;9:e96408.

  • 14 Jeffery ND, Barker AK, Hu HZ, et al. Factors associated with recovery from paraplegia in dogs with loss of pain perception in the pelvic limbs following intervertebral disk herniation. J Am Vet Med Assoc 2016;248:386394.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 15 Fingeroth JM, Thomas WB. Advances in intervertebral disc disease in dog and cats. Danvers, Mass: Wiley Blackwell, 2015;208212.

  • 16 Palamara JD, Bonczynski JJ, Berg JM, et al. Perioperative cefovecin to reduce the incidence of urinary tract infection in dogs undergoing hemilaminectomy. J Am Anim Hosp Assoc 2016;52:297304.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 17 Stiffler KS, Stevenson MA, Sanchez S, et al. Prevalence and characterization of urinary tract infections in dogs with surgically treated type 1 thoracolumbar intervertebral disc extrusion. Vet Surg 2006;35:330336.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 18 Fischer JR, Lane IF, Cribb AE. Urethral pressure profile and hemodynamic effects of phenoxybenzamine and prazosin in non-sedated male Beagle dogs. Can J Vet Res 2003;67:3038.

    • Search Google Scholar
    • Export Citation
  • 19 Andersson K-E. α-Adrenoceptors and benign prostatic hyperplasia: basic principles for treatment with α-adrenoceptor antagonists. World J Urol 2002;19:390396.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 20 Donohoe JM, Combs AJ, Glassberg KI. Primary bladder neck dysfunction in children and adolescents ii: results of treatment with α-adrenergic antagonists. J Urol 2005;173:212216.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 21 Lepor H. Role of α-adrenergic blockers in the treatment of benign prostatic hyperplasia. Prostate Suppl 1990;3:7584.

  • 22 Griffin JF IV, Levine JM, Kerwin SC, et al. Canine thoracolumbar intervertebral disk disease: diagnosis, prognosis, and treatment. Available at: www.vetfolio.com/musculoskeletal/canine-thoracolumbar-intervertebral-disk-disease-diagnosis-prognosis-and-treatment. Accessed May 11, 2018.

    • Search Google Scholar
    • Export Citation
  • 23 Jaggy A, Platt SR. Small animal neurology. Hannover, Germany: Schlütersche, 2010; 178180.

  • 24 Ferreira AJ, Correia JH, Jaggy A. Thoracolumbar disc disease in 71 paraplegic dogs: influence of rate of onset and duration of clinical signs on treatment results. J Small Anim Pract 2002;43:158163.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 25 Ruddle TL, Allen DA, Schertel ER. Outcome and prognostic factors in non-ambulatory Hansen type I intervertebral disc extrusions: 308 cases. Vet Comp Orthop Traumatol 2006;19:2934.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 26 Besalti O, Pekcan Z, Sirin YS, et al. Magnetic resonance imaging findings in dogs with thoracolumbar intervertebral disk disease: 69 cases (1997–2005). J Am Vet Med Assoc 2006;228:902908.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 27 Buttin P, Millet M, Cousin S. Computed tomographic measurements with and without myelography to characterise thoracolumbar extruded disc herniation. J Small Anim Pract 2013;54:521530.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 28 Penning V, Platt SR, Dennis R, et al. Association of spinal cord compression seen on magnetic resonance imaging with clinical outcome in 67 dogs with thoracolumbar intervertebral disc extrusion. J Small Anim Pract 2006;47:644650.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 29 Levine JM, Fosgate GT, Chen AV, et al. Magnetic resonance imaging in dogs with neurologic impairment due to acute thoracic and lumbar intervertebral disk herniation. J Vet Intern Med 2009;23:12201226.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 30 Ito D, Matsunaga S, Jeffery ND, et al. Prognostic value of magnetic resonance imaging in dogs with paraplegia caused by thoracolumbar intervertebral disk extrusion: 77 cases (2000–2003). J Am Vet Med Assoc 2005;227:14541460.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 31 Necnas A. Clinical aspects of surgical treatment of thoracolumbar disc disease in dogs. A retrospective study of 300 cases. Acta Vet Brno 1999;68:121130.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 32 Van Wie EY, Fosgate GT, Mankin JM, et al. Prospectively recorded versus medical record-derived spinal cord injury scores in dogs with intervertebral disk herniation. J Vet Intern Med 2013;27:12731277.

    • Crossref
    • Search Google Scholar
    • Export Citation

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Relationship of preoperative neurologic score with intervals to regaining micturition and ambulation following surgical treatment of thoracolumbar disk herniation in dogs

Ditte SkytteSpine Center, Specialistdjursjukhuset II, 73495 Strömsholm, Sweden.

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Hugo SchmökelSpine Center, Specialistdjursjukhuset II, 73495 Strömsholm, Sweden.

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Abstract

OBJECTIVE To estimate the times required for dogs to regain micturition and ambulation following surgical treatment for thoracolumbar Hansen type I intervertebral disk extrusion (IVDE) and determine whether these variables were associated with preoperative modified Frankel score (MFS).

DESIGN Retrospective case series with nested cohort study.

ANIMALS 54 dogs weighing < 20 kg (44 lb) that were surgically treated for Hansen type I IVDE at a referral hospital between January and December 2015.

PROCEDURES Medical records and CT and MRI data were reviewed. Information was collected regarding dog signalment, type and duration of clinical signs, preoperative MFS, degree of spinal cord compression, type of medical and surgical treatment provided, and intervals from surgery to regaining micturition and ambulation (outcomes). Collected data were evaluated for correlations with outcomes.

RESULTS Mean ± SD interval from surgery to regaining micturition was 4.1 ± 4.4 days, and mean interval from surgery to regaining ambulation was 13.8 ± 25.1 days. These intervals differed significantly. Significant negative correlations with MFS were identified for interval to regaining micturition (r = −0.63) and interval to regaining ambulation (r = −0.64). No other correlations with outcome were identified.

CONCLUSIONS AND CLINICAL RELEVANCE The amount of time required for dogs to regain micturition and ambulation following surgery for thoracolumbar IVDE was correlated with preoperative severity of clinical signs, as reflected by preoperative MFSs. This information should be useful for pre- and postoperative decision-making and setting of expectations for owners of and clinicians treating affected dogs.

Abstract

OBJECTIVE To estimate the times required for dogs to regain micturition and ambulation following surgical treatment for thoracolumbar Hansen type I intervertebral disk extrusion (IVDE) and determine whether these variables were associated with preoperative modified Frankel score (MFS).

DESIGN Retrospective case series with nested cohort study.

ANIMALS 54 dogs weighing < 20 kg (44 lb) that were surgically treated for Hansen type I IVDE at a referral hospital between January and December 2015.

PROCEDURES Medical records and CT and MRI data were reviewed. Information was collected regarding dog signalment, type and duration of clinical signs, preoperative MFS, degree of spinal cord compression, type of medical and surgical treatment provided, and intervals from surgery to regaining micturition and ambulation (outcomes). Collected data were evaluated for correlations with outcomes.

RESULTS Mean ± SD interval from surgery to regaining micturition was 4.1 ± 4.4 days, and mean interval from surgery to regaining ambulation was 13.8 ± 25.1 days. These intervals differed significantly. Significant negative correlations with MFS were identified for interval to regaining micturition (r = −0.63) and interval to regaining ambulation (r = −0.64). No other correlations with outcome were identified.

CONCLUSIONS AND CLINICAL RELEVANCE The amount of time required for dogs to regain micturition and ambulation following surgery for thoracolumbar IVDE was correlated with preoperative severity of clinical signs, as reflected by preoperative MFSs. This information should be useful for pre- and postoperative decision-making and setting of expectations for owners of and clinicians treating affected dogs.

Contributor Notes

Address correspondence to Dr. Schmökel (hugo.schmokel@evidensia.se).