Modification of metabolic responses for cholesterol and other lipids as a result of dietary methods or drugs has been extensively studied in humans and laboratory animals, and much has been published on this topic. However, less is known about this topic in small companion animals, such as dogs and cats. One of the reasons is that compared to humans, cats and dogs are typically resistant to coronary artery disease, myocardial infarction, cerebral vascular stroke, and atherosclerosis. Thus, they are rarely studied in regard to these disorders. Nonetheless, dogs are especially useful in the evaluation of compounds that lead to important