Absolute and relative cell counts for synovial fluid from clinically normal shoulder and stifle joints in cats

Philip D. Pacchiana Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108.
Present address is Fifth Avenue Veterinary Specialists and 24 Hour Emergency Care, 1 W 15th St, New York, NY 10011.

Search for other papers by Philip D. Pacchiana in
Current site
Google Scholar
PubMed
Close
 DVM, MS, DACVS
,
Robert S. Gilley Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108.
Present address is the Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.

Search for other papers by Robert S. Gilley in
Current site
Google Scholar
PubMed
Close
 DVM, PhD, DACVS
,
Larry J. Wallace Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108.

Search for other papers by Larry J. Wallace in
Current site
Google Scholar
PubMed
Close
 DVM, MS, DACVS
,
David W. Hayden Departments of Veterinary Diagnostic Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108.

Search for other papers by David W. Hayden in
Current site
Google Scholar
PubMed
Close
 DVM, PhD, DACVP
,
Daniel A. Feeney Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108.

Search for other papers by Daniel A. Feeney in
Current site
Google Scholar
PubMed
Close
 DVM, DACVR
,
Carl R. Jessen Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108.

Search for other papers by Carl R. Jessen in
Current site
Google Scholar
PubMed
Close
 DVM, PhD, DACVR
, and
Betsy Aird Departments of Veterinary Diagnostic Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108.
Present address is River Valley Farms Inc, 803 Prospect Ave, Osceola, WI 54020.

Search for other papers by Betsy Aird in
Current site
Google Scholar
PubMed
Close
 DVM, PhD, DACVP

Click on author name to view affiliation information

Abstract

Objective—To determine absolute and relative cell counts for synovial fluid from grossly, radiographically, and histologically normal shoulder and stifle joints in healthy cats.

Design—Clinical study.

Animals—52 cats scheduled to be euthanatized for unrelated reasons.

Procedure—Arthrocentesis of the shoulder and stifle joints was performed bilaterally, and synovial fluid was analyzed for absolute WBC count, WBC morphology, and percentages of neutrophils and mononuclear cells. Joints were examined grossly and radiographically, and synovial membrane specimens were submitted for histologic examination. Synovial fluid samples that were contaminated with blood and samples from joints with any gross, radiographic, or histologic abnormalities were excluded.

Results—82 of the 208 synovial fluid samples were excluded because abnormalities were identified during physical examination; the volume of fluid obtained was insufficient for analysis; there was evidence of blood contamination; or the joint had gross, radiographic, or histologic abnormalities. Median WBC count for the remaining 126 synovial fluid samples was 91 cells/μL (96.4% mononuclear cells and 3.6% neutrophils); WBC count was not significantly different between left and right joint samples or between shoulder and stifle joint samples. Body weight was associated with synovial fluid WBC count, with WBC count increasing as body weight increased. Sixteen of the 52 (30%) cats had radiographic evidence of osteoarthritis involving at least 1 joint.

Conclusions and Clinical Relevance—Results suggest that synovial fluid can be obtained reliably from shoulder and stifle joints in cats. (J Am Vet Med Assoc 2004;225:1866–1870)

Abstract

Objective—To determine absolute and relative cell counts for synovial fluid from grossly, radiographically, and histologically normal shoulder and stifle joints in healthy cats.

Design—Clinical study.

Animals—52 cats scheduled to be euthanatized for unrelated reasons.

Procedure—Arthrocentesis of the shoulder and stifle joints was performed bilaterally, and synovial fluid was analyzed for absolute WBC count, WBC morphology, and percentages of neutrophils and mononuclear cells. Joints were examined grossly and radiographically, and synovial membrane specimens were submitted for histologic examination. Synovial fluid samples that were contaminated with blood and samples from joints with any gross, radiographic, or histologic abnormalities were excluded.

Results—82 of the 208 synovial fluid samples were excluded because abnormalities were identified during physical examination; the volume of fluid obtained was insufficient for analysis; there was evidence of blood contamination; or the joint had gross, radiographic, or histologic abnormalities. Median WBC count for the remaining 126 synovial fluid samples was 91 cells/μL (96.4% mononuclear cells and 3.6% neutrophils); WBC count was not significantly different between left and right joint samples or between shoulder and stifle joint samples. Body weight was associated with synovial fluid WBC count, with WBC count increasing as body weight increased. Sixteen of the 52 (30%) cats had radiographic evidence of osteoarthritis involving at least 1 joint.

Conclusions and Clinical Relevance—Results suggest that synovial fluid can be obtained reliably from shoulder and stifle joints in cats. (J Am Vet Med Assoc 2004;225:1866–1870)

All Time Past Year Past 30 Days
Abstract Views 117 0 0
Full Text Views 439 409 81
PDF Downloads 106 83 7
Advertisement