Accuracy of ultrasound-guided fine-needle aspiration of the liver and cytologic findings in dogs and cats: 97 cases (1990–2000)

Kelly Y. Wang Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061.
Present address is the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio 43210.

Search for other papers by Kelly Y. Wang in
Current site
Google Scholar
PubMed
Close
 DVM
,
David L. Panciera Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061.

Search for other papers by David L. Panciera in
Current site
Google Scholar
PubMed
Close
 DVM, MS, DACVIM
,
Raida K. Al-Rukibat Departments of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061.
Present address is the Department of Veterinary Pathology, Jordan University of Science and Technology, Irbid 22110, Jordan.

Search for other papers by Raida K. Al-Rukibat in
Current site
Google Scholar
PubMed
Close
 DVM, MS, DACVP
, and
Zaher A. Radi Departments of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061.
Present address is Veterinary Diagnostic and Investigational Laboratory, University of Georgia, Tifton, GA 31793-3000.

Search for other papers by Zaher A. Radi in
Current site
Google Scholar
PubMed
Close
 DVM, PhD

Abstract

Objective—To evaluate the accuracy of ultrasound-guided fine-needle aspiration of the liver and cytologic findings in dogs and cats.

Design—Retrospective study.

Animals—56 dogs and 41 cats.

Procedure—Medical records of dogs and cats evaluated from 1990 to 2000 by use of cytologic and histopathologic examination of the liver were reviewed. Histologic and cytologic diagnoses were categorized as vacuolar hepatopathy, inflammation, neoplasia, cirrhosis, primary cholestasis, shunt, normal, and other.

Results—Overall agreement between the histopathologic diagnosis and cytologic diagnosis was found in 17 of the 56 (30.3%) canine cases and 21 of the 41 (51.2%) feline cases. Vacuolar hepatopathy was the category with the highest percentage of agreement. Vacuolar hepatopathy was identified via cytologic examination in 7 of 11 and 15 of 18 dogs and cats, respectively, in which histopathologic examination revealed that it was the predominant disease process. However, it was also the category that was most commonly misdiagnosed via cytologic examination. Inflammatory disease was accurately identified cytologically in 5 of 20 and 3 of 11 dogs and cats, respectively.

Conclusions and Clinical Relevance—Acknowledging the limitations of cytology and the extent of discrepancies between cytologic and histopathologic findings in dogs and cats will help clinicians make better decisions in diagnosing liver disease. (J Am Vet Med Assoc 2004; 224:75–78)

Abstract

Objective—To evaluate the accuracy of ultrasound-guided fine-needle aspiration of the liver and cytologic findings in dogs and cats.

Design—Retrospective study.

Animals—56 dogs and 41 cats.

Procedure—Medical records of dogs and cats evaluated from 1990 to 2000 by use of cytologic and histopathologic examination of the liver were reviewed. Histologic and cytologic diagnoses were categorized as vacuolar hepatopathy, inflammation, neoplasia, cirrhosis, primary cholestasis, shunt, normal, and other.

Results—Overall agreement between the histopathologic diagnosis and cytologic diagnosis was found in 17 of the 56 (30.3%) canine cases and 21 of the 41 (51.2%) feline cases. Vacuolar hepatopathy was the category with the highest percentage of agreement. Vacuolar hepatopathy was identified via cytologic examination in 7 of 11 and 15 of 18 dogs and cats, respectively, in which histopathologic examination revealed that it was the predominant disease process. However, it was also the category that was most commonly misdiagnosed via cytologic examination. Inflammatory disease was accurately identified cytologically in 5 of 20 and 3 of 11 dogs and cats, respectively.

Conclusions and Clinical Relevance—Acknowledging the limitations of cytology and the extent of discrepancies between cytologic and histopathologic findings in dogs and cats will help clinicians make better decisions in diagnosing liver disease. (J Am Vet Med Assoc 2004; 224:75–78)

Advertisement