Chronic granulocytic leukemia in a dog

Deborah M. Fine From the Departments of Small Animal Clinical Sciences (Fine) and Pathology (Tvedten), College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824-1314.

Search for other papers by Deborah M. Fine in
Current site
Google Scholar
PubMed Close
 DVM
and
Harold W. Tvedten From the Departments of Small Animal Clinical Sciences (Fine) and Pathology (Tvedten), College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824-1314.

Search for other papers by Harold W. Tvedten in
Current site
Google Scholar
PubMed Close
 DVM, PhD
DOI:
https://doi.org/10.2460/javma.1999.214.12.1809
Volume/Issue:
Volume 214: Issue 12
Online Publication Date:
15 Jun 1999
Free access
Sign In Reprints and Permissions

  • Chronic granulocytic leukemia is an uncommon myeloproliferative disorder that results in substantial proliferation of mature granulocytes.

  • Because the severe leukocytosis and left shift observed with chronic granulocytic leukemia may strongly resemble a leukemoid reaction, other causes of severe leukocytosis must be ruled out.

  • Myeloid cellular infiltrations may cause hepatomegaly, splenomegaly, or nonregenerative anemia and thrombocytopenia.

  • Commonly, results of serum biochemical analyses are only minimally altered or within reference ranges and clinical signs are nonspecific.

  • Chronic granulocytic leukemia is an uncommon myeloproliferative disorder that results in substantial proliferation of mature granulocytes.

  • Because the severe leukocytosis and left shift observed with chronic granulocytic leukemia may strongly resemble a leukemoid reaction, other causes of severe leukocytosis must be ruled out.

  • Myeloid cellular infiltrations may cause hepatomegaly, splenomegaly, or nonregenerative anemia and thrombocytopenia.

  • Commonly, results of serum biochemical analyses are only minimally altered or within reference ranges and clinical signs are nonspecific.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 707 687 20
PDF Downloads 166 150 12
Cover Journal of the American Veterinary Medical Association
Journal of the American Veterinary Medical Association
Publication Date:
15 Jun 1999
Advertisement