Retinal degeneration associated with vitamin E deficiency in hunting dogs

M. G. Davidson From the Departments of Companion Animals and Special Species Medicine (Davidson, Gilger), and Microbiology, Pathology, and Parasitology (Geoly), College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606; Department of Small Animal Medicine and Surgery, Royal Veterinary College, University of London, North Mymms, Hertfordshire, England (McLellan); and Berkeley Veterinary Clinic, 1102 N Berkeley Blvd, Goldsboro, NC 27534 (Whitley).

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F J. Geoly From the Departments of Companion Animals and Special Species Medicine (Davidson, Gilger), and Microbiology, Pathology, and Parasitology (Geoly), College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606; Department of Small Animal Medicine and Surgery, Royal Veterinary College, University of London, North Mymms, Hertfordshire, England (McLellan); and Berkeley Veterinary Clinic, 1102 N Berkeley Blvd, Goldsboro, NC 27534 (Whitley).

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B. C. Gilger From the Departments of Companion Animals and Special Species Medicine (Davidson, Gilger), and Microbiology, Pathology, and Parasitology (Geoly), College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606; Department of Small Animal Medicine and Surgery, Royal Veterinary College, University of London, North Mymms, Hertfordshire, England (McLellan); and Berkeley Veterinary Clinic, 1102 N Berkeley Blvd, Goldsboro, NC 27534 (Whitley).

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G. J. McLellan From the Departments of Companion Animals and Special Species Medicine (Davidson, Gilger), and Microbiology, Pathology, and Parasitology (Geoly), College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606; Department of Small Animal Medicine and Surgery, Royal Veterinary College, University of London, North Mymms, Hertfordshire, England (McLellan); and Berkeley Veterinary Clinic, 1102 N Berkeley Blvd, Goldsboro, NC 27534 (Whitley).

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W. Whitley From the Departments of Companion Animals and Special Species Medicine (Davidson, Gilger), and Microbiology, Pathology, and Parasitology (Geoly), College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606; Department of Small Animal Medicine and Surgery, Royal Veterinary College, University of London, North Mymms, Hertfordshire, England (McLellan); and Berkeley Veterinary Clinic, 1102 N Berkeley Blvd, Goldsboro, NC 27534 (Whitley).

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  • Nutritional deficiency of vitamin E in dogs can lead to oxidative damage and degeneration of the photoreceptors of the retina.

  • Clinical and pathologic changes associated with vitamin E deficiency in dogs are similar to those described for central progressive retinal atrophy and equine lower motor neuron disease, which suggests that these diseases share a common pathogenesis.

  • Nutritional deficiency of vitamin E in dogs can lead to oxidative damage and degeneration of the photoreceptors of the retina.

  • Clinical and pathologic changes associated with vitamin E deficiency in dogs are similar to those described for central progressive retinal atrophy and equine lower motor neuron disease, which suggests that these diseases share a common pathogenesis.

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