In animals with cancer, clinical signs that are not directly related to local or distant spread of the tumor are considered paraneoplastic.
Reported paraneoplastic disorders in horses with lymphoma include fever, hypercalcemia, and anemia.
Paraneoplastic pruritus and alopecia can develop in people with lymphoma; furthermore, lymphoma should be considered in the differential diagnoses when examining horses with generalized pruritus for which another cause cannot be identified.
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