Renal transplants in cats: 66 cases (1987–1996)

Kyle G. Mathews From the Department of Surgical and Radiological Sciences (Mathews), and Comparative Transplantation Laboratory (Gregory), School of Veterinary Medicine, University of California, Davis, CA 95616-8734.

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Clare R. Gregory From the Department of Surgical and Radiological Sciences (Mathews), and Comparative Transplantation Laboratory (Gregory), School of Veterinary Medicine, University of California, Davis, CA 95616-8734.

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Objective

To document the morbidity and survival time after renal transplants in cats with end-stage renal failure.

Design

Retrospective case series.

Animals

66 cats that had renal transplants.

Procedure

Information regarding signalment, history, diagnostic testing, and postoperative morbidity and mortality was retrieved from medical records of cats with renal failure that had renal transplants at the University of California School of Veterinary Medicine between 1987 and 1996.

Results

47 of 66 (71%) cats that had renal transplants survived until discharge. Nineteen cats died in the perioperative period. Most common causes of death were seizure-related complications (7 cats) and renal pedicle complications (4). One discharged cat was unavailable for follow-up monitoring. Of the 46 cats discharged and available for follow-up monitoring, 28 died. Most common causes of death in these cats were renal complications (9 cats) and death related to immunosuppression (8; mean and median survival times, 15 and 12 months, respectively). Of the 18 cats that were still living at the time this report was written, mean and median survival times were 26 and 22 months, respectively.

Clinical Implications

Renal transplantation resulted in long-term survival of many cats that would have otherwise died from, or have been euthanatized as a result of, renal failure. Problems with ureteral obstruction can be minimized. Postoperative CNS disorders were the most prevalent complication. (J Am Vet Med Assoc 1997;211:1432–1436)

Objective

To document the morbidity and survival time after renal transplants in cats with end-stage renal failure.

Design

Retrospective case series.

Animals

66 cats that had renal transplants.

Procedure

Information regarding signalment, history, diagnostic testing, and postoperative morbidity and mortality was retrieved from medical records of cats with renal failure that had renal transplants at the University of California School of Veterinary Medicine between 1987 and 1996.

Results

47 of 66 (71%) cats that had renal transplants survived until discharge. Nineteen cats died in the perioperative period. Most common causes of death were seizure-related complications (7 cats) and renal pedicle complications (4). One discharged cat was unavailable for follow-up monitoring. Of the 46 cats discharged and available for follow-up monitoring, 28 died. Most common causes of death in these cats were renal complications (9 cats) and death related to immunosuppression (8; mean and median survival times, 15 and 12 months, respectively). Of the 18 cats that were still living at the time this report was written, mean and median survival times were 26 and 22 months, respectively.

Clinical Implications

Renal transplantation resulted in long-term survival of many cats that would have otherwise died from, or have been euthanatized as a result of, renal failure. Problems with ureteral obstruction can be minimized. Postoperative CNS disorders were the most prevalent complication. (J Am Vet Med Assoc 1997;211:1432–1436)

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