Five-year longitudinal study on limited food consumption and development of osteoarthritis in coxofemoral joints of dogs

Richard Dean Kealy From Pet Products Research and Development (Kealy, Lawler) and the Ralston Analytical Laboratories (Ballam), Ralston Purina Co, Checkerboard Sq, St Louis, MO 63164; the James A. Baker Institute for Animal Health, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 (Lust); the Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 (Biery, Smith); and the Laboratory for Comparative Pathology, Wentholmes Gard, S-170 17 Farentuna, Sweden (Olsson).

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Dennis Frank Lawler From Pet Products Research and Development (Kealy, Lawler) and the Ralston Analytical Laboratories (Ballam), Ralston Purina Co, Checkerboard Sq, St Louis, MO 63164; the James A. Baker Institute for Animal Health, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 (Lust); the Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 (Biery, Smith); and the Laboratory for Comparative Pathology, Wentholmes Gard, S-170 17 Farentuna, Sweden (Olsson).

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Joan Marion Ballam From Pet Products Research and Development (Kealy, Lawler) and the Ralston Analytical Laboratories (Ballam), Ralston Purina Co, Checkerboard Sq, St Louis, MO 63164; the James A. Baker Institute for Animal Health, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 (Lust); the Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 (Biery, Smith); and the Laboratory for Comparative Pathology, Wentholmes Gard, S-170 17 Farentuna, Sweden (Olsson).

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George Lust From Pet Products Research and Development (Kealy, Lawler) and the Ralston Analytical Laboratories (Ballam), Ralston Purina Co, Checkerboard Sq, St Louis, MO 63164; the James A. Baker Institute for Animal Health, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 (Lust); the Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 (Biery, Smith); and the Laboratory for Comparative Pathology, Wentholmes Gard, S-170 17 Farentuna, Sweden (Olsson).

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Gail Keen Smith From Pet Products Research and Development (Kealy, Lawler) and the Ralston Analytical Laboratories (Ballam), Ralston Purina Co, Checkerboard Sq, St Louis, MO 63164; the James A. Baker Institute for Animal Health, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 (Lust); the Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 (Biery, Smith); and the Laboratory for Comparative Pathology, Wentholmes Gard, S-170 17 Farentuna, Sweden (Olsson).

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Daryl Norman Biery From Pet Products Research and Development (Kealy, Lawler) and the Ralston Analytical Laboratories (Ballam), Ralston Purina Co, Checkerboard Sq, St Louis, MO 63164; the James A. Baker Institute for Animal Health, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 (Lust); the Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 (Biery, Smith); and the Laboratory for Comparative Pathology, Wentholmes Gard, S-170 17 Farentuna, Sweden (Olsson).

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Sten Eric Olsson From Pet Products Research and Development (Kealy, Lawler) and the Ralston Analytical Laboratories (Ballam), Ralston Purina Co, Checkerboard Sq, St Louis, MO 63164; the James A. Baker Institute for Animal Health, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 (Lust); the Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 (Biery, Smith); and the Laboratory for Comparative Pathology, Wentholmes Gard, S-170 17 Farentuna, Sweden (Olsson).

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Objective

To examine the effects of limited food intake on frequency and severity of osteoarthritis in coxofemoral joints of Labrador Retrievers.

Design

Dogs were paired according to gender and body weight, within each litter, at 8 weeks of age. One dog of each pair was fed ad libitum. The limit-fed pairmate was fed 75% of the amount eaten the previous day by the ad libitum-fed counterpart.

Animals

48 Labrador Retrievers.

Procedure

All dogs received the same diet. Radiographic evaluation of coxofemoral joints for frequency and severity of osteoarthritis were made when dogs were 4 and 6 months and 1, 2, 3, and 5 years old.

Results

Radiographic evaluation for osteoarthritis indicated greater frequency and more severity of osteoarthritis in the ad libitum-fed group of dogs.

Clinical Implications

Analysis of data suggested that limit feeding of dogs over a 5-year period minimizes development of osteoarthritis in the coxofemoral joints.

Objective

To examine the effects of limited food intake on frequency and severity of osteoarthritis in coxofemoral joints of Labrador Retrievers.

Design

Dogs were paired according to gender and body weight, within each litter, at 8 weeks of age. One dog of each pair was fed ad libitum. The limit-fed pairmate was fed 75% of the amount eaten the previous day by the ad libitum-fed counterpart.

Animals

48 Labrador Retrievers.

Procedure

All dogs received the same diet. Radiographic evaluation of coxofemoral joints for frequency and severity of osteoarthritis were made when dogs were 4 and 6 months and 1, 2, 3, and 5 years old.

Results

Radiographic evaluation for osteoarthritis indicated greater frequency and more severity of osteoarthritis in the ad libitum-fed group of dogs.

Clinical Implications

Analysis of data suggested that limit feeding of dogs over a 5-year period minimizes development of osteoarthritis in the coxofemoral joints.

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