Ocular blastomycosis in dogs: 73 cases, 108 eyes (1985–1993)

Jonathan D. Bloom From the Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61801.

Search for other papers by Jonathan D. Bloom in
Current site
Google Scholar
PubMed
Close
 DVM
,
Ralph E. Hamor From the Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61801.

Search for other papers by Ralph E. Hamor in
Current site
Google Scholar
PubMed
Close
 DVM, MS
, and
Paul A. Gerding Jr. From the Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61801.

Search for other papers by Paul A. Gerding Jr. in
Current site
Google Scholar
PubMed
Close
 DVM, MS

Click on author name to view affiliation information

Objective

To evaluate clinical signs of ocular blastomycosis in dogs, to determine response of blastomycosis-infected eyes to treatment with systemically administered amphotericin B and ketoconazole, and to identify prognostic indicators of successful antifungal treatment.

Design

Retrospective study.

Animals

73 dogs.

Procedure

Medical records were reviewed for all dogs with confirmed blastomycosis and ocular disease seen at our hospital between 1985 and 1993.

Results

6 eyes had anterior segment disease, 24 had posterior segment disease, and 78 had endophthalmitis. 40 eyes were treated with a combination of amphotericin B and ketoconazole, and 16 of the 40 responded favorably. However, 16 of the 24 eyes that were not severely affected responded favorably, but none of the 16 eyes that were severely affected did.

Clinical Implications

Dogs with blastomycosis had posterior segment disease, without complete retinal separation, had a good prognosis for retaining vision. Results of histologic examination suggested that secondary glaucoma was a manifestation of endophthalmitis and was indicative of a grave prognosis for response to antifungal and antiglaucoma treatment. (J Am Vet Med Assoc 1996;209:1271–1274)

Objective

To evaluate clinical signs of ocular blastomycosis in dogs, to determine response of blastomycosis-infected eyes to treatment with systemically administered amphotericin B and ketoconazole, and to identify prognostic indicators of successful antifungal treatment.

Design

Retrospective study.

Animals

73 dogs.

Procedure

Medical records were reviewed for all dogs with confirmed blastomycosis and ocular disease seen at our hospital between 1985 and 1993.

Results

6 eyes had anterior segment disease, 24 had posterior segment disease, and 78 had endophthalmitis. 40 eyes were treated with a combination of amphotericin B and ketoconazole, and 16 of the 40 responded favorably. However, 16 of the 24 eyes that were not severely affected responded favorably, but none of the 16 eyes that were severely affected did.

Clinical Implications

Dogs with blastomycosis had posterior segment disease, without complete retinal separation, had a good prognosis for retaining vision. Results of histologic examination suggested that secondary glaucoma was a manifestation of endophthalmitis and was indicative of a grave prognosis for response to antifungal and antiglaucoma treatment. (J Am Vet Med Assoc 1996;209:1271–1274)

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 433 433 105
PDF Downloads 52 52 8
Advertisement