Effect of tiletamine/zolazepam sedation on intradermal allergy testing in atopic dogs

Ellen C. Codner From the Departments of Small Animal Clinical Sciences (Codner, McGrath) and Large Animal Clinical Sciences (Lessard), Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.

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Pierre Lessard From the Departments of Small Animal Clinical Sciences (Codner, McGrath) and Large Animal Clinical Sciences (Lessard), Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.

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Charles J. McGrath From the Departments of Small Animal Clinical Sciences (Codner, McGrath) and Large Animal Clinical Sciences (Lessard), Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.

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Summary

Seven atopic dogs underwent intradermal allergy testing with 46 inhalant antigens before and after administration of a tiletamine/zolazepam solution (4 mg/kg of body weight, IV). This anesthetic protocol had no significant effect on the intradermal response caused by histamine, whole flea extract, or various inhalant allergens. Short-acting chemical restraint induced by the drug combination facilitated the intradermal testing procedure.

Summary

Seven atopic dogs underwent intradermal allergy testing with 46 inhalant antigens before and after administration of a tiletamine/zolazepam solution (4 mg/kg of body weight, IV). This anesthetic protocol had no significant effect on the intradermal response caused by histamine, whole flea extract, or various inhalant allergens. Short-acting chemical restraint induced by the drug combination facilitated the intradermal testing procedure.

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