Treatment of pyometra in cats, using prostaglandin F: 21 cases (1982-1990)

Autumn P. Davidson From the Small Animal Internal Medicine Service, Veterinary Medical Teaching Hospital (Davidson), and the Departments of Reproduction (Feldman) and Medicine (Nelson), School of Veterinary Medicine, University of California, Davis, CA 95616.

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Edward C. Feldman From the Small Animal Internal Medicine Service, Veterinary Medical Teaching Hospital (Davidson), and the Departments of Reproduction (Feldman) and Medicine (Nelson), School of Veterinary Medicine, University of California, Davis, CA 95616.

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Richard W. Nelson From the Small Animal Internal Medicine Service, Veterinary Medical Teaching Hospital (Davidson), and the Departments of Reproduction (Feldman) and Medicine (Nelson), School of Veterinary Medicine, University of California, Davis, CA 95616.

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Summary

Treatment with prostaglandin F (pgf) was evaluated in 21 queens with open-cervix pyometra. The pgf was administered (0.1 or 0.25 mg/kg of body weight, sc, q 12 to 24 h) for 3 or 5 days. Transient postinjection reactions caused by pgf administration included vocalization, panting, restlessness, grooming, tenesmus, salivation, diarrhea, kneading, mydriasis, emesis, urination, and lordosis. Reactions began as quickly as 30 seconds after pgf administration and lasted as long as 60 minutes. All queens improved clinically after pgf treatment. One month after completion of the initial series, 1 queen required a second series of pgf injections before pyometra resolved. Of 21 queens, 20 (95%) resumed normal estrous cycles without further treatment and 17 (81%) delivered normal litter(s). Use of pgf is an acceptable treatment for open-cervix pyometra in queens.

Summary

Treatment with prostaglandin F (pgf) was evaluated in 21 queens with open-cervix pyometra. The pgf was administered (0.1 or 0.25 mg/kg of body weight, sc, q 12 to 24 h) for 3 or 5 days. Transient postinjection reactions caused by pgf administration included vocalization, panting, restlessness, grooming, tenesmus, salivation, diarrhea, kneading, mydriasis, emesis, urination, and lordosis. Reactions began as quickly as 30 seconds after pgf administration and lasted as long as 60 minutes. All queens improved clinically after pgf treatment. One month after completion of the initial series, 1 queen required a second series of pgf injections before pyometra resolved. Of 21 queens, 20 (95%) resumed normal estrous cycles without further treatment and 17 (81%) delivered normal litter(s). Use of pgf is an acceptable treatment for open-cervix pyometra in queens.

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