Positive end-expiratory pressure (peep) was applied in 74 anesthetized, ventilated horses during colic surgery, to attempt to increase arterial oxygen tensions. In 28 horses with an initial
Cardiovascular depression and decrease in arterial blood pressure was observed after the application of peep in 54 horses. These 54 horses required use of pressors (n = 8), inotropes (n = 32), or both (n = 14) to keep the mean arterial blood pressure > 60 mm of Hg. Combined with pharmacologic support of blood pressure, peep could be a useful clinical treatment of arterial hypoxemia in horses.
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