Treatment of Trichophyton mentagrophytes infection in rabbits

C. L. Franklin From the Research Animal Diagnostic and Investigative Laboratory and the Department of Veterinary Pathology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211.

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S. V. Gibson From the Research Animal Diagnostic and Investigative Laboratory and the Department of Veterinary Pathology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211.

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C. J. Caffrey From the Research Animal Diagnostic and Investigative Laboratory and the Department of Veterinary Pathology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211.

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J. E. Wagner From the Research Animal Diagnostic and Investigative Laboratory and the Department of Veterinary Pathology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211.

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E. K. Steffen From the Research Animal Diagnostic and Investigative Laboratory and the Department of Veterinary Pathology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211.

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Summary

Copper sulfate and a metastabilized chlorous acid/chlorine dioxide (meca) compound were evaluated for efficacy in treating Trichophyton mentagrophytes infection in rabbits. Forty rabbits naturally infected with T mentagrophytes were allotted to 5 treatment groups: nontreated control, sham dip, 1% copper sulfate dip, meca dip, and meca spray. Results of lesion culture, regression of gross lesions, and histopathologic findings were documented. Copper sulfate and meca were effective in treating clinical dermatophytosis and in decreasing T mentagrophytes carrier status in rabbits.

Summary

Copper sulfate and a metastabilized chlorous acid/chlorine dioxide (meca) compound were evaluated for efficacy in treating Trichophyton mentagrophytes infection in rabbits. Forty rabbits naturally infected with T mentagrophytes were allotted to 5 treatment groups: nontreated control, sham dip, 1% copper sulfate dip, meca dip, and meca spray. Results of lesion culture, regression of gross lesions, and histopathologic findings were documented. Copper sulfate and meca were effective in treating clinical dermatophytosis and in decreasing T mentagrophytes carrier status in rabbits.

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