Treatment of atrial fibrillation in horses by intravenous administration of quinidine

William W. Muir III From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210-1089.

Search for other papers by William W. Muir III in
Current site
Google Scholar
PubMed
Close
 DVM, PhD
,
Stephen M. Reed From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210-1089.

Search for other papers by Stephen M. Reed in
Current site
Google Scholar
PubMed
Close
 DVM
, and
Sheila M. McGuirk From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210-1089.

Search for other papers by Sheila M. McGuirk in
Current site
Google Scholar
PubMed
Close
 DVM

Click on author name to view affiliation information

Summary

Intravenous administration of quinidine gluconate converted atrial fibrillation (af) to sinus rhythm in 9 of 12 horses. Twelve horses that were diagnosed by ecg to have af were administered up to 11 mg of quinidine gluconate/kg of body weight in 1.0 -to 1.5-mg/kg bolus injections every 10 to 15 minutes. The total dose of quinidine administered iv ranged from 1.8 to 5.8 g. Increased ventricular rate, apprehension, and mild depression were observed during treatment. Other signs of toxicosis were not observed. One horse was successfully treated with iv administered quinidine gluconate on 3 occasions. Intravenous administration of quinidine is a safe and effective alternative for treatment of af in some horses.

Summary

Intravenous administration of quinidine gluconate converted atrial fibrillation (af) to sinus rhythm in 9 of 12 horses. Twelve horses that were diagnosed by ecg to have af were administered up to 11 mg of quinidine gluconate/kg of body weight in 1.0 -to 1.5-mg/kg bolus injections every 10 to 15 minutes. The total dose of quinidine administered iv ranged from 1.8 to 5.8 g. Increased ventricular rate, apprehension, and mild depression were observed during treatment. Other signs of toxicosis were not observed. One horse was successfully treated with iv administered quinidine gluconate on 3 occasions. Intravenous administration of quinidine is a safe and effective alternative for treatment of af in some horses.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 171 171 73
PDF Downloads 53 53 14
Advertisement