Enhancing the health of animals through antimicrobial stewardship research

David R. Smith Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS

Search for other papers by David R. Smith in
Current site
Google Scholar
PubMed
Close
 DVM, PhD, DACVPM
,
Alicia K. Olivier Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS

Search for other papers by Alicia K. Olivier in
Current site
Google Scholar
PubMed
Close
 DVM, PhD, DACVP
, and
Melody H. Thurlow College of Veterinary Medicine, Mississippi State University, Mississippi State, MS

Search for other papers by Melody H. Thurlow in
Current site
Google Scholar
PubMed
Close
 BA

Click on author name to view affiliation information

The Mississippi State University College of Veterinary Medicine (MSU CVM) is at the forefront of researching antimicrobial stewardship to protect and improve the health of diverse animal species.

Cattle

Dr. Amelia Woolums’ laboratory at MSU CVM showed tulathromycin metaphylaxis reduced the proportion of high-risk cattle treated for bovine respiratory disease (BRD) after arrival. However, cattle receiving metaphylaxis were more likely to shed multidrug-resistant (MDR) bacteria. This finding reveals an ethical dilemma, in that metaphylaxis improved health in cattle at high risk for BRD, but with increased detection of MDR.

Drs. David Smith, Isaac Jumper, Robert Wills, and Kimberly Woodruff are designing an easy-to-use smartphone application for recording cattle health events and antimicrobial use to improve antimicrobial stewardship.

Drs. Isaac Jumper and David Smith are researching risk factors for bovine anaplasmosis on cow-calf operations and methods of detection without intensive handling, with a goal of identifying prevention and control practices that are alternatives to antimicrobial use.

Honeybees

Drs. Kimberly Woodruff, MSU CVM, and Priya Basu, MSU College of Agriculture and Life Sciences, are developing a testing method that speeds detection of European foulbrood and avoids stressing the bees by opening the hive.

Aquaculture

The MSU Global Center for Aquatic Health and Food Security serves as the Food and Agriculture Organization reference center for antimicrobial resistance (AMR) in fish. Drs. Mark Lawrence and Hasan Tekedar use adaptive laboratory evolution to identify genetic adaptations fish pathogens use to develop AMR. Dr. Hossam Abdelhamed’s laboratory is working to mitigate the prevalence of multidrug-resistant bacterial strains in the aquatic environment by understanding molecular mechanisms of resistance in bacteria isolated from catfish.

F1

Researchers at MSU are improving animal health through the investigation of antimicrobial resistance and stewardship.

Citation: American Journal of Veterinary Research 85, 5; 10.2460/ajvr.24.03.0063

Companion animals

Outbreaks of carbapenem-resistant enterobacterales (CRE) infections at MSU CVM and elsewhere prompted MSU CVM researchers Drs. Cooper Brookshire, Keun Seo, and Joo Youn Park to develop an interdisciplinary translational research program with other collaborators for CRE surveillance, and clinical management of infections in veterinary species.

Conclusion

The MSU CVM is making great strides in research related to antimicrobial resistance and stewardship. We are committed to improving animal health while extending the effectiveness of antimicrobials.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 481 481 83
PDF Downloads 305 305 42
Advertisement