Book Reviews

Pharmacotherapeutics for Veterinary Dispensing

Katrina L. Mealey, BS (Pharm), DVM, PhD, DACVIM, DACVCP

623 pages. 2019. Wiley Blackwell. ISBN 978-1-119-40454-5. Price $149.99.

Pharmacotherapeutics for Veterinary Dispensing is a book long overdue for the pharmacy profession. The text is organized in an intuitive manner. Subject content is well thought out and provides readers a thorough informational foundation that will be an asset to pharmacists. This book should be a required reference for pharmacists who have not had any training in veterinary pharmacy but fill veterinary prescriptions. The information in this book is presented in a manner that will be easily navigated and understood by any pharmacist. Chapters dedicated to subject matter other than pharmacology provide background information necessary for traditionally trained pharmacists to understand how veterinary pharmacy differs from human pharmacy and why it is important to understand regulatory issues as well as species-specific nuances. The contributing authors are recognized experts, which lends credibility to the text. Extensive references provide validity to concepts presented throughout each chapter. A chapter addressing compounding for veterinary patients is appropriately included. The first 5 chapters establish the foundation on which the remainder of the book rests. The appendices are well thought out and appropriate and contain valuable information. The use of shaded boxes to call attention to points of emphasis is effective and not overdone. This book will be an excellent reference for both pharmacy students and pharmacists. Whether you have practiced veterinary pharmacy your whole career or have never practiced veterinary pharmacy, this book has much to offer. Veterinarians are encouraged to suggest this book to pharmacists with whom they work and interact.

Reviewed by Wil Gwin, RPh, DICVP

Purdue Veterinary Teaching Hospital Pharmacy West Lafayette, Ind

Chemical Hazards in Foods of Animal Origin (Volume 7: Food Safety Assurance and Veterinary Public Health Series)

Frans J. M. Smulders, DVM, PhD, DECVPH; Ivonne M. C. M. Rietjens, PhD; & Martin D. Rose, BSc, PhD

669 pages. 2019. Wageningen Academic Publishers. ISBN 978-90-8686-326-6. Price $220.00.

Food is the primary route by which humans are exposed to many agricultural and industrial chemicals. Chemical Hazards in Foods of Animal Origin provides toxicological information and risk assessments for many chemical hazards in foods of animal origin from the perspectives of members of the European Food Safety Authority. It is a compilation of 25 chapters from 65 authors. The book begins with an excellent overview of risk analysis, plus a note on the role of veterinarians. Chapters on avoidable chemicals address veterinary drug residues, pesticides, feed additives, and food contact materials. The section on unavoidable chemical contaminants includes metals, phytotoxins, mycotoxins, and heat processing–related contaminants in feeds, among other topics. The book continues with a section on hazards associated with particular food categories, which provides readers with an in-depth look at risks in meat, dairy products, fish, eggs, and honey. The book concludes with several interesting and well-known case studies including fraudulent food situations.

This volume provides up-to-date and useful information on food hazards by means of a useful framework of avoidable and inherent chemicals in food and food products of animal origin. It will be a worthy addition to the library of any veterinarian involved in public health practice as well as all veterinary school libraries.

Reviewed by Candace A. Jacobs, DVM, MPH, DACVPM

Kulshan Services Olympia, Wash

The Welfare of Cattle

Terry Engle, PhD; Donald J. Klingborg, DVM; & Bernard E. Rollin, PhD

345 pages. 2019. CRC Press (an imprint of Taylor & Francis Group). ISBN 978-1-138-19706-1. Price $99.95.

Veterinarians are in a position to be strong advocates for the welfare of food animals. Consumers are increasingly interested and becoming more vocal about their preferences in how their food is raised. Veterinarians are uniquely placed at the intersection between consumer demand for higher welfare standards and economic realities for producers. The Welfare of Cattle is a comprehensive textbook that can be used as a reference for welfare issues facing the cattle industry today. This book represents the culmination of constructive dialogue among cattle welfare experts, with the intention of providing readers with a basic understanding of contemporary cattle production and how issues regarding cattle welfare are evolving.

The book is divided into 4 parts. The first part consists of a series of 7 white papers from notable cattle welfare experts and sets the tone for the rest of the book. Topics covered in the white papers include the sustainability of the cattle industry, climate change, and use of biotechnology to improve animal welfare. The second part of the book covers concepts relevant to both beef and dairy cattle. The chapter on pain mitigation will be of particular interest to veterinarians. The third and fourth parts of the book focus on welfare concerns specific to the beef and dairy industries, respectively.

Bovine practitioners who are already immersed in the world of cattle welfare may find this book too basic. This book would have been more impactful for bovine veterinarians had it included a more intense discussion and thoughtful plan on how to achieve welfare aims in the future. Nevertheless, this book is still worth reading. It was written by notable leaders in the area of cattle welfare, and they certainly achieved their goal of creating a comprehensive source of information on current welfare issues faced by the cattle industry.

Reviewed by Erin King, DVM

Tufts University North Grafton, Mass

Advances in Pig Welfare

Marek Ŝpinka, Doc RNDr, CSc

492 pages. 2018. Woodhead Publishing (an imprint of Elsevier). ISBN 978-0-08-101012-9. Price $140.00.

Advances in Pig Welfare provides historical and prospective information about the science of swine welfare for veterinarians in the field of swine production medicine. Moreover, the topics covered in this book are highly applicable to all stakeholders across the food chain, including retailers, restaurateurs, researchers, packers, policy makers, and, yes, farmers and producers.

The book is divided into 2 sections. The first section consists of 10 chapters that provide a thorough review of welfare issues during the pig production cycle from farrowing to slaughter. Some of the issues reviewed include sow welfare in farrowing crates, piglet mortality, the physical and social environment of piglets, tail biting, enrichment, hunger in pregnant sows, aggression in grouped sows and pigs, transport, and slaughter. Each chapter has an extensive review of the literature and provides the authors' conclusions regarding the current state of knowledge on the topic being presented and suggestions for future research or challenges to be addressed.

The second section of the book focuses on 6 emerging topics of pig welfare that are extremely relevant for the future improvement of welfare in the swine industry. The 6 topics include pain, welfare assessments by use of animal-based measures, the pig-human interaction, genetic impact on welfare, positive pig welfare, and welfare of pigs used in research.

Each chapter provides readers with an excellent overview of up-to-date science as it relates to swine welfare. I find the chapter on positive pig welfare particularly thought provoking because intensive pig production and the evaluation of pig welfare in intensive production systems are evolving rapidly. Overall, this is an extremely well-researched and written book regarding the current state of swine welfare.

Reviewed by Angela Baysinger, DVM, MS

North American Animal Welfare Lead Merck Animal Health Bruning, Neb

Porcine Viruses: From Pathogenesis to Strategies for Control

Hovakim Zakaryan, PhD

201 pages. 2019. Caister Academic Press. ISBN 978-1-910190-91-3. Price $319.00.

Porcine Viruses: From Pathogenesis to Strategies for Control is a suitable resource for anyone working with pig viruses, including PhD students, scientists, and veterinarians. The book, written by international swine experts, is organized into 8 chapters, which cover African swine fever virus, classical swine fever virus, foot-and-mouth disease virus, porcine circoviruses, porcine epidemic diarrhea virus, porcine parvoviruses, porcine reproductive and respiratory syndrome virus, and swine vesicular virus.

Overall, this book is a compact reference for some of the most important viral infections currently circulating in pig populations. At first glance, the book title and cover image would suggest that this book targets veterinarians and control strategies. However, upon reading, it becomes evident that the emphasis is on molecular and cellular virus biology. The text is often very technical and may be hard to follow for readers without extensive background knowledge on the subject. Therefore, this book may be of greatest value to virologists and others working in closely related sciences. Descriptions of clinical signs are scant, and pictures of typical lesions are not provided for all viruses discussed. Veterinary students who are starting to learn about viral diseases in pigs may benefit from reading certain sections but may become overwhelmed by the amount of background information provided. The reasoning regarding which viruses were included in this book is unclear. For example, influenza A virus and pseudorabies virus, among others, are not discussed. Finally, the book is high priced, especially given that not all important viral infections present in today's pigs are covered.

Reviewed by Tanja Opriessnig, Dr med vet, PhD

Roslin Institute University of Edinburgh Midlothian, Scotland and Iowa State University Ames, Iowa

The Common Marmoset in Captivity and Biomedical Research (American College of Laboratory Animal Medicine Series)

Robert P. Marini, DVM, DACLAM; Lynn M. Wachtman, DVM, MPH; Suzette D. Tardif, PhD; Keith Mansfield, DVM, DACVP; & James G. Fox, DVM, MS, DACLAM

555 pages. 2019. Academic Press (an imprint of Elsevier). ISBN 978-0-12-811829-0. Price $164.50.

The Common Marmoset in Captivity and Bio-medical Research, a recent addition to the American College of Laboratory Animal Medicine Series, represents a comprehensive review of the anatomy, biology, behavior, care, and management of common marmosets (Callithrix jacchus). Most importantly, it presents a thorough discussion of the application of common marmosets in biomedical research. This book is the result of an international effort, and it provides an in-depth review of the common marmoset including numerous excellent illustrations, particularly in the anatomy and neuroanatomy sections. Members of the Callitrichidae family have been used variably in biomedical research for the past 50 years, but the use of marmosets for research purposes has increased substantially in the last decade, particularly in the fields of neuroscience, aging, infectious disease, and, most recently, gene editing technology. The chapter on creating genetically modified marmosets provides an excellent discussion of the application of endo-nucleases, such as zinc finger nucleases (ZFNs), transcription activator–like effector nucleases (TALENs), and the clustered regularly interspaced short palindromic repeats (CRISPR) Cas9 system, to nonhuman primates and the inherent advantages in the biology of marmosets. The Research Applications section contains detailed and well-written discussions about future areas of research investigation. The chapter on marmoset aging includes management advice for geriatric marmosets.

Historically, macaques have been the predominant species used for nonhuman primate research. Recognition of the broad application of marmosets in diverse research fields, combined with emergence of transgenic nonhuman primates, has stimulated tremendous interest in the use of marmosets in biomedical research. This book will be an invaluable reference for colony managers, veterinarians, behaviorists, and investigators involved in the care, propagation, and research application of common marmosets. Moreover, the value of this book extends beyond the biomedical research community because its contents cover the broad topic of the natural history of common marmosets, which will be of interest to the zoological and conservation communities as well.

Reviewed by Jeffrey A. Roberts, DVM, DACLAM

University of California-Davis Davis, Calif

Electrocardiography of Laboratory Animals (2nd edition)

Jeffrey W. Richig, DVM, Meg M. Sleeper, VMD, DACVIM

110 pages. 2019. Academic Press (an imprint of Elsevier). ISBN 978-0-12-809469-3. Price $213.00.

The second edition of Electrocardiography of Laboratory Animals provides a basic and excellent introduction to obtaining and interpreting ECGs in a variety of common laboratory animal species. The book begins with an overview regarding the need for the acquisition of high-quality ECGs as a means to include or exclude individual animals in preclinical safety studies. There is a good summary regarding electrophysiology and ECG basics. Impressively, there are countless examples of ECGs, including normal ECGs, normal ECG variants observed among species, and many different types of arrhythmias.

This book will be useful for laboratory animal researchers, veterinarians, veterinary technicians, and veterinary and graduate students as well as researchers who are studying potential cardiotoxic effects of new treatments. The authors have appropriately built on the foundation of the first edition with the addition of new pearls of wisdom and experience in obtaining and interpreting ECGs of laboratory animals.

Reviewed by Katherine Hogan, DVM, DACVIM

Angell Animal Medical Center Boston, Mass

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