Book Reviews

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Textbook of Veterinary Physiological Chemistry (3rd edition)

Larry R. Engelking

773 pages. 2014. Academic Press (an imprint of Elsevier). ISBN 978-0-12-391909-0. Price $99.95.

The third edition of the Textbook of Veterinary Physiological Chemistry is an outstanding reference for anyone who needs to tie physiology, biochemistry, nutrition, and disease together. The book succinctly addresses many topics including protein synthesis, fat metabolism, nutrition, and acid-base balance. It is laid out logically with concise chapters that interweave physiology with biochemistry.

To fully appreciate the text, readers need to have some prior knowledge of general chemistry and physiology. The book contains many physiology examples, and naïve readers will likely have difficulty following the text. However, this book will be a valuable resource to help students integrate material when used as a companion textbook for a physiology course.

One of the strengths of this book is its ability to relate biochemistry to disease conditions. The sections on nutrients outline the roles of specific nutrients in biochemical pathways then delineate how the absence or excess of a specific nutrient leads to clinical disease. Differences in biochemical pathways among species and breeds are also described, although that information is in various locations throughout the text. Regardless, the text will help students understand and appreciate necessary differences in pharmacotherapy among species.

Each chapter ends with a set of objectives and several fact-based, multiple-choice questions for self-assessment. The end of each section contains multiple-choice review questions along with the answers to those questions. Most graphs and illustrations are simple, 2-color flow charts or tables. The text is written simply without much elaboration. However, it contains many abbreviations, and the overuse of abbreviations in conjunction with the frequent bolding of words within the text is distracting and may cause some readers to miss the take-home point being conveyed because they are trying to determine what a particular abbreviation means or why a specific word is bolded.

Overall, this book is an excellent textbook that is filled with facts that will aid readers in understanding veterinary physiology, pharmacology, nutrition, and biochemistry. It is a strong addition to the veterinary literature.

Reviewed by James Herman, DVM, PhD

Texas A&M University

Pathology of the Developing Mouse: A Systematic Approach

Brad Bolon

430 pages. 2015. CRC Press (an imprint of Taylor & Francis Group). ISBN 978-1-4200-7008-8. Price $119.95.

Pathology of the Developing Mouse: A Systematic Approach is a much anticipated addition to the veterinary pathology reference literature. It is a fairly inexpensive textbook that will be useful for anyone who uses mice in developmental research.

As stated in chapter 1, “This book is designed for the developmental pathologist in us all.” The material presented will help beginning researchers involved in developmental biology as well as comparative pathologists and developmental biologists who already have considerable experience.

The book is well organized into sections, beginning with an introduction that has an excellent description of the background and importance of using mice in developmental biology research and the need for developmental pathologists. This is followed by sections entitled Mouse Developmental Biology Fundamentals, Experimental Methods in Mouse Developmental Pathology, and Mouse Developmental Pathology Analysis. All topics are covered well and include baseline anatomy and physiology, experimental design and statistics, anatomic pathology examination procedures, clinical pathology methods, and appropriate terminology for normal structures and lesions.

Detailed, easy-to-follow experimental protocols are described throughout the text. In many cases, there are multiple options for procedures with pros and cons discussed for each. Each chapter contains excellent tables, diagrams, and photographs and ends with a complete reference list.

Although there is a growing volume of information on mouse developmental biology in the literature and on the Internet, the authors of this book have done a great job of creating a synopsis of this information that can be easily used by anyone working or training in mouse pathology or developmental biology.

Reviewed by Stephen M. Griffey, DVM, PhD

University of California-Davis, Davis, Calif

The Care and Feeding of an IACUC: The Organization and Management of an Institutional Animal Care and Use Committee (2nd edition)

Whitney Kayla Petrie & Sonja Lea Wallace

364 pages. 2015. CRC Press (an imprint of Taylor & Francis Group). ISBN 978-1-4822-0110-9. Price $89.95.

Having served on IACUCs in academia, industry, and biotech sectors for over 15 years, I recommend the second edition of The Care and Feeding of an IACUC: The Organization and Management of an Institutional Animal Care and Use Committee as a must-read for anyone who has the privilege of serving on an IACUC. I have worked with and personally know several of this book's authors and contributors, and collectively, they have done an excellent job compiling a well-written, straightforward, and easy-to-understand narrative. The information presented is clear and concise and provides readers with a big-picture overview of the role, responsibilities, and significance of an IACUC as well as the role it plays in facilitating research efforts and outcomes.

I found the tables in this book particularly useful for comparing the different regulatory stipulations surrounding the IACUC. I was particularly intrigued by the chapter on the role and power of the outside or nonaffiliated member on the IACUC because, in my experience, that individual often does not view himself or herself as having a substantial role or power on the committee.

Not once while reading this book did I feel overwhelmed or bored by the information conveyed. On the contrary, I kept thinking how useful this resource would have been at the start of my career in the field of biomedical research. I strongly recommend that this book be required reading for everyone serving on an IACUC, regardless of how experienced they may be, because I believe everyone can glean something useful from the information presented.

Reviewed by Laike St. A. Stewart, DVM, DACLAM

University of Miami, Miami, Fla

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