Changes in rectal temperature and hematologic, biochemical, blood gas, and acid-base values in healthy Labrador Retrievers before and after strenuous exercise

Cary L. Matwichuk From the Departments of Veterinary Internal Medicine (Matwichuk, Taylor) and Veterinary Anesthesia, Radiology and Surgery (Shmon), Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada, S7N 5B4; the Section of Biometrics and Preventive Medicine, Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616-8737 (Kass); and the Comparative Neuromuscular Laboratory, Department of Pathology, University of California, San Diego, La Jolla, CA 92093-0612 (Shelton).

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Susan M. Taylor From the Departments of Veterinary Internal Medicine (Matwichuk, Taylor) and Veterinary Anesthesia, Radiology and Surgery (Shmon), Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada, S7N 5B4; the Section of Biometrics and Preventive Medicine, Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616-8737 (Kass); and the Comparative Neuromuscular Laboratory, Department of Pathology, University of California, San Diego, La Jolla, CA 92093-0612 (Shelton).

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Cindy L. Shmon From the Departments of Veterinary Internal Medicine (Matwichuk, Taylor) and Veterinary Anesthesia, Radiology and Surgery (Shmon), Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada, S7N 5B4; the Section of Biometrics and Preventive Medicine, Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616-8737 (Kass); and the Comparative Neuromuscular Laboratory, Department of Pathology, University of California, San Diego, La Jolla, CA 92093-0612 (Shelton).

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Philip H. Kass From the Departments of Veterinary Internal Medicine (Matwichuk, Taylor) and Veterinary Anesthesia, Radiology and Surgery (Shmon), Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada, S7N 5B4; the Section of Biometrics and Preventive Medicine, Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616-8737 (Kass); and the Comparative Neuromuscular Laboratory, Department of Pathology, University of California, San Diego, La Jolla, CA 92093-0612 (Shelton).

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G. Diane Shelton From the Departments of Veterinary Internal Medicine (Matwichuk, Taylor) and Veterinary Anesthesia, Radiology and Surgery (Shmon), Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada, S7N 5B4; the Section of Biometrics and Preventive Medicine, Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616-8737 (Kass); and the Comparative Neuromuscular Laboratory, Department of Pathology, University of California, San Diego, La Jolla, CA 92093-0612 (Shelton).

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Abstract

Objective

To measure changes in rectal temperature and hematologic, biochemical, blood gas, and acid-base values before and after exercise.

Animals

14 healthy adult Labrador Retrievers.

Procedure

Dogs exercised continuously for 10 minutes by repeatedly retrieving a dummy thrown approximately 40 to 50 yards on land. The ambient temperature during each exercise period was recorded. Rectal temperature, pulse, and respiratory rate were measured; CBC and serum biochemical profile were determined; and arterial blood gas tensions, acid-base status, and plasma lactate and pyruvate concentrations were measured at rest and immediately after exercise. Rectal temperature, pulse, respiratory rate, and lactate and pyruvate concentrations were evaluated at intervals up to 120 minutes after exercise.

Results

Immediately after exercise, rectal temperature increased markedly; ambient temperature did not affect rectal temperature. Arterial blood pH and Pao2 were significantly increased after exercise, and Paco2 and bicarbonate concentration were significantly decreased after exercise. Also, statistically, but not clinically, significant increases were observed in RBC, WBC, and segmented neutrophil counts; hemoglobin, total protein, and serum sodium and potassium concentrations; PCV; anion gap; and creatine kinase activity. Plasma lactate and pyruvate concentrations increased significantly after exercise, but there was no change in the lactate-to-pyruvate ratio.

Conclusion and Clinical Relevance

Reference values for healthy Laborador Retrievers during a standardized exercise protocol were established to compare data obtained from Laborador Retrievers with exercise intolerance and collapse. Important characteristics of lactate and pyruvate metabolism were documented that will enable more precise evaluation of exercise intolerance in this breed. (Am J Vet Res 1999;60:88–92)

Abstract

Objective

To measure changes in rectal temperature and hematologic, biochemical, blood gas, and acid-base values before and after exercise.

Animals

14 healthy adult Labrador Retrievers.

Procedure

Dogs exercised continuously for 10 minutes by repeatedly retrieving a dummy thrown approximately 40 to 50 yards on land. The ambient temperature during each exercise period was recorded. Rectal temperature, pulse, and respiratory rate were measured; CBC and serum biochemical profile were determined; and arterial blood gas tensions, acid-base status, and plasma lactate and pyruvate concentrations were measured at rest and immediately after exercise. Rectal temperature, pulse, respiratory rate, and lactate and pyruvate concentrations were evaluated at intervals up to 120 minutes after exercise.

Results

Immediately after exercise, rectal temperature increased markedly; ambient temperature did not affect rectal temperature. Arterial blood pH and Pao2 were significantly increased after exercise, and Paco2 and bicarbonate concentration were significantly decreased after exercise. Also, statistically, but not clinically, significant increases were observed in RBC, WBC, and segmented neutrophil counts; hemoglobin, total protein, and serum sodium and potassium concentrations; PCV; anion gap; and creatine kinase activity. Plasma lactate and pyruvate concentrations increased significantly after exercise, but there was no change in the lactate-to-pyruvate ratio.

Conclusion and Clinical Relevance

Reference values for healthy Laborador Retrievers during a standardized exercise protocol were established to compare data obtained from Laborador Retrievers with exercise intolerance and collapse. Important characteristics of lactate and pyruvate metabolism were documented that will enable more precise evaluation of exercise intolerance in this breed. (Am J Vet Res 1999;60:88–92)

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