Effect of craniectomy/durotomy alone and in combination with hyperventilation, diuretics, and corticosteroids on intracranial pressure in clinically normal dogs

Rodney S. Bagley From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Michael L. Harrington From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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G. Elizabeth Pluhar From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Robert D. Keegan From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Stephen A. Greene From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Michael P. Moore From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Patrick R. Gavin From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Abstract

Objective

To determine the effect of craniectomy and durotomy on intracranial pressure (ICP) in clinically normal dogs.

Design

Two-part study (experiments A and B) involving craniectomy and durotomy, with and without treatments to lower ICP.

Animals

Six (experiment A) and 7 (experiment B) healthy dogs.

Procedure

In experiment A, craniectomy was performed in combination with durotomy, diuretic administration, methylprednisolone sodium succinate administration, and hyperventilation, and effect of these manipulations on ICP was determined. In experiment B, dogs had only craniectomy and durotomy without associated ICP-lowering treatments. During both experiments, ICP was monitored throughout the surgical procedure with a fiber optic ICP monitoring device.

Results

Intracranial pressure decreased after the combination of craniectomy, durotomy, and other ICP-lowering treatments in dogs of experiment A. Similar magnitude of decrease in ICP was observed in dogs of experiment B after craniectomy and durotomy.

Conclusions

Comparison of these experiments indicate that surgical removal of overlying skull and incision of the dura mater can significantly decrease ICP in clinically normal dogs.

Clinical Relevance

Craniectomy and durotomy may be useful as an adjunct treatment for increased ICP. (Am J Vet Res 1996;57:116-119)

Abstract

Objective

To determine the effect of craniectomy and durotomy on intracranial pressure (ICP) in clinically normal dogs.

Design

Two-part study (experiments A and B) involving craniectomy and durotomy, with and without treatments to lower ICP.

Animals

Six (experiment A) and 7 (experiment B) healthy dogs.

Procedure

In experiment A, craniectomy was performed in combination with durotomy, diuretic administration, methylprednisolone sodium succinate administration, and hyperventilation, and effect of these manipulations on ICP was determined. In experiment B, dogs had only craniectomy and durotomy without associated ICP-lowering treatments. During both experiments, ICP was monitored throughout the surgical procedure with a fiber optic ICP monitoring device.

Results

Intracranial pressure decreased after the combination of craniectomy, durotomy, and other ICP-lowering treatments in dogs of experiment A. Similar magnitude of decrease in ICP was observed in dogs of experiment B after craniectomy and durotomy.

Conclusions

Comparison of these experiments indicate that surgical removal of overlying skull and incision of the dura mater can significantly decrease ICP in clinically normal dogs.

Clinical Relevance

Craniectomy and durotomy may be useful as an adjunct treatment for increased ICP. (Am J Vet Res 1996;57:116-119)

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