Evaluation of hemorheologic variables as implications for exercise-induced pulmonary hemorrhage in racing Thoroughbreds
Carolyn B. McClay
 DVM
Carolyn B. McClay
From the Departments of Veterinary Pathobiology (McClay, Weiss) and Large Animal Clinical Sciences (Gordon), College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Ave, St Paul, MN 55108, and the Department of Pediatrics (Smith), School of Medicine, University of Minnesota, Minneapolis, MN 55455.
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Douglas J. Weiss
 DVM, PhD
Douglas J. Weiss
From the Departments of Veterinary Pathobiology (McClay, Weiss) and Large Animal Clinical Sciences (Gordon), College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Ave, St Paul, MN 55108, and the Department of Pediatrics (Smith), School of Medicine, University of Minnesota, Minneapolis, MN 55455.
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Clark M. Smith II
 MD
Clark M. Smith II
From the Departments of Veterinary Pathobiology (McClay, Weiss) and Large Animal Clinical Sciences (Gordon), College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Ave, St Paul, MN 55108, and the Department of Pediatrics (Smith), School of Medicine, University of Minnesota, Minneapolis, MN 55455.
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Brad Gordon
 DVM
Brad Gordon
From the Departments of Veterinary Pathobiology (McClay, Weiss) and Large Animal Clinical Sciences (Gordon), College of Veterinary Medicine, University of Minnesota, 1971 Commonwealth Ave, St Paul, MN 55108, and the Department of Pediatrics (Smith), School of Medicine, University of Minnesota, Minneapolis, MN 55455.
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Summary
Hematologic and rheologic changes were examined in 49 Thoroughbreds before and after competitive racing. Mean postrace values for rbc count, hemoglobin concentration, and pcv increased by 58 to 61%, whereas blood viscosity increased 2 to 3 times. Postrace echinocyte numbers were 162% greater than prerace values. Smaller, but statistically significant, changes were found for mean corpuscular hemoglobin concentration, red cell distribution width, plasma total protein concentration, total wbc count, neutrophil count, and lymphocyte count. Variables measured did not predict whether a horse was a bleeder not treated with furosemide, a bleeder treated with furosemide, or a nonbleeder.
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