Efficacy of two formulations of albendazole against liver flukes in cattle

T. M. Craig From the Department of Veterinary Microbiology and Parasitology, Texas A&M University, College Station, TX 77843 (Craig, Qureshi, Miller, Wade), and SmithKline Beecham Animal Health, 1600 Paoli Pike, West Chester, PA 19380 (Rogers).

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 DVM, PhD
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T. Qureshi From the Department of Veterinary Microbiology and Parasitology, Texas A&M University, College Station, TX 77843 (Craig, Qureshi, Miller, Wade), and SmithKline Beecham Animal Health, 1600 Paoli Pike, West Chester, PA 19380 (Rogers).

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D. K. Miller From the Department of Veterinary Microbiology and Parasitology, Texas A&M University, College Station, TX 77843 (Craig, Qureshi, Miller, Wade), and SmithKline Beecham Animal Health, 1600 Paoli Pike, West Chester, PA 19380 (Rogers).

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C. G. Wade From the Department of Veterinary Microbiology and Parasitology, Texas A&M University, College Station, TX 77843 (Craig, Qureshi, Miller, Wade), and SmithKline Beecham Animal Health, 1600 Paoli Pike, West Chester, PA 19380 (Rogers).

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J. A. Rogers From the Department of Veterinary Microbiology and Parasitology, Texas A&M University, College Station, TX 77843 (Craig, Qureshi, Miller, Wade), and SmithKline Beecham Animal Health, 1600 Paoli Pike, West Chester, PA 19380 (Rogers).

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Summary

Albendazole (10 mg/kg of body weight) was administered as a drench suspension or as a feed additive to 24 cattle with naturally acquired infections of Fasciola hepatica and Fascioloides magna. Cattle were euthanatized 16 to 30 days after treatment, and the number of viable flukes was counted. Viable F hepatica and F magna were decreased by 91.4% and 70.6% for drench administration and by 82.9% and 71.9% for the feed additive treatment, respectively. There was no significant difference between the efficacy of the 2 formulations in decreasing viable fluke numbers, compared with untreated controls.

Summary

Albendazole (10 mg/kg of body weight) was administered as a drench suspension or as a feed additive to 24 cattle with naturally acquired infections of Fasciola hepatica and Fascioloides magna. Cattle were euthanatized 16 to 30 days after treatment, and the number of viable flukes was counted. Viable F hepatica and F magna were decreased by 91.4% and 70.6% for drench administration and by 82.9% and 71.9% for the feed additive treatment, respectively. There was no significant difference between the efficacy of the 2 formulations in decreasing viable fluke numbers, compared with untreated controls.

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