Effects of estradiol 17ß implants on hematologic values and the chemiluminescence response of neutrophils of steers

K. L. Angel From the Department of Large Animal Surgery and Medicine (Angel, Schumacher, Wolfe, Tyler, Carson), College of Veterinary Medicine, and USDA – ARS, Animal Parasite Research Laboratory (Klesius), Auburn University, Al 36849-5522.

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J. Schumacher From the Department of Large Animal Surgery and Medicine (Angel, Schumacher, Wolfe, Tyler, Carson), College of Veterinary Medicine, and USDA – ARS, Animal Parasite Research Laboratory (Klesius), Auburn University, Al 36849-5522.

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D. F. Wolfe From the Department of Large Animal Surgery and Medicine (Angel, Schumacher, Wolfe, Tyler, Carson), College of Veterinary Medicine, and USDA – ARS, Animal Parasite Research Laboratory (Klesius), Auburn University, Al 36849-5522.

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P. H. Kleeiue From the Department of Large Animal Surgery and Medicine (Angel, Schumacher, Wolfe, Tyler, Carson), College of Veterinary Medicine, and USDA – ARS, Animal Parasite Research Laboratory (Klesius), Auburn University, Al 36849-5522.

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J. W. Tyler From the Department of Large Animal Surgery and Medicine (Angel, Schumacher, Wolfe, Tyler, Carson), College of Veterinary Medicine, and USDA – ARS, Animal Parasite Research Laboratory (Klesius), Auburn University, Al 36849-5522.

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R. L. Carson From the Department of Large Animal Surgery and Medicine (Angel, Schumacher, Wolfe, Tyler, Carson), College of Veterinary Medicine, and USDA – ARS, Animal Parasite Research Laboratory (Klesius), Auburn University, Al 36849-5522.

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Summary

The effects of subcutaneous administration of a commercially available estradiol 17ß implant on hematologic values and the chemiluminescence response of neutrophils were evaluated in 14 steers. Chemiluminescence and hematologic values were measured in treated (n = 8) and nontreated (n = 6) steers on days – 14, – 7, and – 1 prior to implantation. Estradiol 17ß was implanted into the treated group of steers on day 0, and blood samples were obtained from all steers on days 1, 2, 3, 4, 8, 15, 22, 29, 36, 43, and 50. The concentration of estrogen in serum was significantly (P = 0.0120) higher following implantation. Chemiluminescence and hematologic indices were not significantly affected by either implant status or serum concentrations of estrogen. The results of this study suggested that the use of implants containing estradiol 17ß for promotion of weight gain in steers will not result in alterations of hematologic values or the neutrophil respiratory burst.

Summary

The effects of subcutaneous administration of a commercially available estradiol 17ß implant on hematologic values and the chemiluminescence response of neutrophils were evaluated in 14 steers. Chemiluminescence and hematologic values were measured in treated (n = 8) and nontreated (n = 6) steers on days – 14, – 7, and – 1 prior to implantation. Estradiol 17ß was implanted into the treated group of steers on day 0, and blood samples were obtained from all steers on days 1, 2, 3, 4, 8, 15, 22, 29, 36, 43, and 50. The concentration of estrogen in serum was significantly (P = 0.0120) higher following implantation. Chemiluminescence and hematologic indices were not significantly affected by either implant status or serum concentrations of estrogen. The results of this study suggested that the use of implants containing estradiol 17ß for promotion of weight gain in steers will not result in alterations of hematologic values or the neutrophil respiratory burst.

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