Functional analysis of ectopic parathyroid activity in cats

J. A. Flanders From the Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853

Search for other papers by J. A. Flanders in
Current site
Google Scholar
PubMed
Close
 DVM
,
S. Neth From the Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853

Search for other papers by S. Neth in
Current site
Google Scholar
PubMed
Close
 DVM
,
H. N. Erb From the Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853

Search for other papers by H. N. Erb in
Current site
Google Scholar
PubMed
Close
 DVM, PhD
, and
F. A. Kallfelz From the Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853

Search for other papers by F. A. Kallfelz in
Current site
Google Scholar
PubMed
Close
 DVM, PhD

Summary

The ability of ectopic parathyroid tissue to support calcium homeostasis was evaluated by measuring serum concentrations of calcium, phosphorus, albumin, magnesium, and parathyroid hormone before and for 12 weeks after bilateral thyroparathyroidectomy in 14 cats. During the immediate postoperative period, significant decrease was observed in serum calcium, magnesium, and parathyroid hormone (pth) concentrations. Serum pth concentration remained subnormal and did not significantly increase during the 12-week observation period. Despite persistent hypoparathyroidism, serum calcium and magnesium concentrations gradually increased. Ectopic parathyroid tissue is not capable of maintaining normal serum calcium concentration immediately after thyroparathyroidectomy. Serum calcium concentration gradually normalizes after thyroparathyroidectomy, apparently by means of a pth-independent mechanism.

Summary

The ability of ectopic parathyroid tissue to support calcium homeostasis was evaluated by measuring serum concentrations of calcium, phosphorus, albumin, magnesium, and parathyroid hormone before and for 12 weeks after bilateral thyroparathyroidectomy in 14 cats. During the immediate postoperative period, significant decrease was observed in serum calcium, magnesium, and parathyroid hormone (pth) concentrations. Serum pth concentration remained subnormal and did not significantly increase during the 12-week observation period. Despite persistent hypoparathyroidism, serum calcium and magnesium concentrations gradually increased. Ectopic parathyroid tissue is not capable of maintaining normal serum calcium concentration immediately after thyroparathyroidectomy. Serum calcium concentration gradually normalizes after thyroparathyroidectomy, apparently by means of a pth-independent mechanism.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 3455 3430 48
PDF Downloads 67 45 5
Advertisement