Quantitative electroencephalography in dogs anesthetized with 2.0% end-tidal concentration of isoflurane anesthesia

Michael P. Moore From the Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Stephen A. Greene From the Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Robert D. Keegan From the Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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LeRoy Gallagher From the Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Patrick R. Gavin From the Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Susan L. Kraft From the Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Constance DeHaan From the Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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Kurt Klappenbach From the Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610.

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SUMMARY

Quantitative electroencephalography was assessed in dogs under controlled, 2% end-tidal isoflurane anesthetic conditions, and each variable at each electrode site was tested for normal distribution. With the quantitative electroencephalographic system used, 16 values for each of 21 electrode sites were evaluated. Absolute power ratios also were evaluated. The methods for quantitative electroencephalographic recording and analysis appear to be readily adaptable to the dog. Most of the data do not conform to a normal distribution. Therefore, distribution- free nonparametric statistics should be used when looking for differences under experimental or clinical conditions. Quantitative electroencephalography appears to be a sensitive noninvasive method that could be used to evaluate brain function under anesthetic, clinical, and experimental settings.

SUMMARY

Quantitative electroencephalography was assessed in dogs under controlled, 2% end-tidal isoflurane anesthetic conditions, and each variable at each electrode site was tested for normal distribution. With the quantitative electroencephalographic system used, 16 values for each of 21 electrode sites were evaluated. Absolute power ratios also were evaluated. The methods for quantitative electroencephalographic recording and analysis appear to be readily adaptable to the dog. Most of the data do not conform to a normal distribution. Therefore, distribution- free nonparametric statistics should be used when looking for differences under experimental or clinical conditions. Quantitative electroencephalography appears to be a sensitive noninvasive method that could be used to evaluate brain function under anesthetic, clinical, and experimental settings.

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