Seroprevalence of ovine progressive pneumonia virus in various domestic and wild animal species, and species susceptibility to the virus

Randall C. Cutlip From the National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, PO Box 70, Ames, IA 50010.

Search for other papers by Randall C. Cutlip in
Current site
Google Scholar
PubMed
Close
 DVM, PhD
,
Howard D. Lehmkuhl From the National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, PO Box 70, Ames, IA 50010.

Search for other papers by Howard D. Lehmkuhl in
Current site
Google Scholar
PubMed
Close
 PhD
,
Kim A. Brogden From the National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, PO Box 70, Ames, IA 50010.

Search for other papers by Kim A. Brogden in
Current site
Google Scholar
PubMed
Close
 PhD
, and
Mary Jo F. Schmerr From the National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, PO Box 70, Ames, IA 50010.

Search for other papers by Mary Jo F. Schmerr in
Current site
Google Scholar
PubMed
Close
 PhD

SUMMARY

Ovine progressive pneumonia is caused by a lentivirus of known infectivity only for sheep and goats. Virus susceptibility of 11 other species of animals was examined. Species included cattle, chickens, deer, dogs, goats, hamsters, horses, mice, pigs, rabbits, and rats. Of these species, only goats and rabbits could be experimentally infected with the virus. The infection in rabbits was acute, and virus did not persist or induce antibody production as it does in sheep and goats. Sera obtained from several people working in close contact with the virus and from several wild species, with unknown exposure history, were tested for antibodies to viral antigens. All results were negative. Knowledge of the host range of this virus is important for scientific studies and for virus eradication programs.

SUMMARY

Ovine progressive pneumonia is caused by a lentivirus of known infectivity only for sheep and goats. Virus susceptibility of 11 other species of animals was examined. Species included cattle, chickens, deer, dogs, goats, hamsters, horses, mice, pigs, rabbits, and rats. Of these species, only goats and rabbits could be experimentally infected with the virus. The infection in rabbits was acute, and virus did not persist or induce antibody production as it does in sheep and goats. Sera obtained from several people working in close contact with the virus and from several wild species, with unknown exposure history, were tested for antibodies to viral antigens. All results were negative. Knowledge of the host range of this virus is important for scientific studies and for virus eradication programs.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 6118 6118 1567
PDF Downloads 63 63 1
Advertisement