Variable suppression of feline bone marrow fibroblast colony-forming units by two isolates of feline leukemia virus

Maxey L. Wellman From the Department of Veterinary Pathobiology, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Rd, Columbus, OH 43210.

Search for other papers by Maxey L. Wellman in
Current site
Google Scholar
PubMed
Close
 DVM, PhD
,
Gary J. Kociba From the Department of Veterinary Pathobiology, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Rd, Columbus, OH 43210.

Search for other papers by Gary J. Kociba in
Current site
Google Scholar
PubMed
Close
 DVM, PhD
, and
Larry E. Mathes From the Department of Veterinary Pathobiology, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Rd, Columbus, OH 43210.

Search for other papers by Larry E. Mathes in
Current site
Google Scholar
PubMed
Close
 PhD

Click on author name to view affiliation information

SUMMARY

Bone marrow fibroblast colony-forming units (cfu-f) were evaluated in cats experimentally infected with different isolates of FeLV. Cats infected with the Kawa-kami-Theilen isolate of FeLV (FeLV-KT) had progressive decrease in the number of cfu-f at 2, 4, and 6 weeks after infection. The number of cfu-f in FeLV-KT-infected cats ranged from 38 to 70% of the preinoculation cfu-f value. Of 3 cats with FeLV-KT-induced suppression of cfu-f, 2 developed fatal nonregenerative anemia. Cats infected with the Rickard isolate of FeLV (FeLV-R) had more moderate decrease in the number of cfu-f at 2, 4, and 6 weeks after infection. The number of cfu-f in FeLV-R-infected cats ranged from 62 to 82% of the preinoculation cfu-f value. The FeLV-R-infected cats did not become anemic.

SUMMARY

Bone marrow fibroblast colony-forming units (cfu-f) were evaluated in cats experimentally infected with different isolates of FeLV. Cats infected with the Kawa-kami-Theilen isolate of FeLV (FeLV-KT) had progressive decrease in the number of cfu-f at 2, 4, and 6 weeks after infection. The number of cfu-f in FeLV-KT-infected cats ranged from 38 to 70% of the preinoculation cfu-f value. Of 3 cats with FeLV-KT-induced suppression of cfu-f, 2 developed fatal nonregenerative anemia. Cats infected with the Rickard isolate of FeLV (FeLV-R) had more moderate decrease in the number of cfu-f at 2, 4, and 6 weeks after infection. The number of cfu-f in FeLV-R-infected cats ranged from 62 to 82% of the preinoculation cfu-f value. The FeLV-R-infected cats did not become anemic.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 38 38 18
PDF Downloads 20 20 4
Advertisement