Cardiopulmonary effects of butorphanol tartrate intravenously administered for placement of duodenal cannulae in isoflurane-anesthetized yearling steers

J. L. Cornick From the Departments of Large Animal Medicine and Surgery (Taylor) and Small Animal Medicine and Surgery (Cronick, Hartsfield, Jacobson), Texas Veterinary Medical Center, College of Veterinary Medicine, Texas A&M University, College Station, TX 77840.

Search for other papers by J. L. Cornick in
Current site
Google Scholar
PubMed
Close
 DVM, MS
,
S. M. Hartsfield From the Departments of Large Animal Medicine and Surgery (Taylor) and Small Animal Medicine and Surgery (Cronick, Hartsfield, Jacobson), Texas Veterinary Medical Center, College of Veterinary Medicine, Texas A&M University, College Station, TX 77840.

Search for other papers by S. M. Hartsfield in
Current site
Google Scholar
PubMed
Close
 DVM, MS
,
T. S. Taylor From the Departments of Large Animal Medicine and Surgery (Taylor) and Small Animal Medicine and Surgery (Cronick, Hartsfield, Jacobson), Texas Veterinary Medical Center, College of Veterinary Medicine, Texas A&M University, College Station, TX 77840.

Search for other papers by T. S. Taylor in
Current site
Google Scholar
PubMed
Close
 DVM, MS
, and
J. Jacobson From the Departments of Large Animal Medicine and Surgery (Taylor) and Small Animal Medicine and Surgery (Cronick, Hartsfield, Jacobson), Texas Veterinary Medical Center, College of Veterinary Medicine, Texas A&M University, College Station, TX 77840.

Search for other papers by J. Jacobson in
Current site
Google Scholar
PubMed
Close
 DVM

Click on author name to view affiliation information

SUMMARY

Cardiopulmonary effects of iv administered butorphanol tartrate (but) were assessed in 7 yearling steers medicated with atropine and anesthetized with guaifenesin, thiamylal sodium, and isoflurane in O2 for surgical placement of duodenal cannulae. Heart rate, respiratory rate, arterial blood pressures, pHa, Paco2, Pao2 arterial [HCO3-], esophageal temperature, and end-tidal isoflurane concentrations were measured before and after iv administration of but (10 mg).

Mean respiratory rate increased significantly (P < 0.05) only at 45 and 60 minutes after but administration. Mean respiratory rate was 26 ± 6.3 breaths/min before but administration and 46 ± 12.1 breaths/min 60 minutes after but administration. Arterial blood pressures were increased significantly (P < 0.05) at all times, except 5 minutes after but administration. The mean value for mean arterial pressure was 76 ± 9.6 mm of Hg before but injection and 117 ± 12.6 mm of Hg 60 minutes after but injection. Mean values for pHa and arterial [HCO3-] were significantly (P < 0.05) higher at 60 minutes after but administration (baseline, pH = 7.25 ± 0.04 and [HCO3-] = 29.9 ± 3.5 mEq/L; 60 minutes after but, pH = 7.28 ± 0.03 and [HCO3-] = 33.0 ± 1.8 mEq/L). Although some statistically significant changes were recorded, iv administration of but to these steers did not have a marked effect on the cardiopulmonary variables measured.

SUMMARY

Cardiopulmonary effects of iv administered butorphanol tartrate (but) were assessed in 7 yearling steers medicated with atropine and anesthetized with guaifenesin, thiamylal sodium, and isoflurane in O2 for surgical placement of duodenal cannulae. Heart rate, respiratory rate, arterial blood pressures, pHa, Paco2, Pao2 arterial [HCO3-], esophageal temperature, and end-tidal isoflurane concentrations were measured before and after iv administration of but (10 mg).

Mean respiratory rate increased significantly (P < 0.05) only at 45 and 60 minutes after but administration. Mean respiratory rate was 26 ± 6.3 breaths/min before but administration and 46 ± 12.1 breaths/min 60 minutes after but administration. Arterial blood pressures were increased significantly (P < 0.05) at all times, except 5 minutes after but administration. The mean value for mean arterial pressure was 76 ± 9.6 mm of Hg before but injection and 117 ± 12.6 mm of Hg 60 minutes after but injection. Mean values for pHa and arterial [HCO3-] were significantly (P < 0.05) higher at 60 minutes after but administration (baseline, pH = 7.25 ± 0.04 and [HCO3-] = 29.9 ± 3.5 mEq/L; 60 minutes after but, pH = 7.28 ± 0.03 and [HCO3-] = 33.0 ± 1.8 mEq/L). Although some statistically significant changes were recorded, iv administration of but to these steers did not have a marked effect on the cardiopulmonary variables measured.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 32 32 9
PDF Downloads 23 23 1
Advertisement