Reference intervals for feline cerebrospinal fluid: Cell counts and cytologic features

Jacqueline S. Rand From the Departments of Clinical Studies (Rand, Parent) and Pathology (Jacobs, Percy), Ontario Veterinary College, University of Guelph, Guelph, Ontario, NIG 2W1, Canada.

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 BVSc, DVSc
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Joane Parent From the Departments of Clinical Studies (Rand, Parent) and Pathology (Jacobs, Percy), Ontario Veterinary College, University of Guelph, Guelph, Ontario, NIG 2W1, Canada.

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 DVM, MSc
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Robert Jacobs From the Departments of Clinical Studies (Rand, Parent) and Pathology (Jacobs, Percy), Ontario Veterinary College, University of Guelph, Guelph, Ontario, NIG 2W1, Canada.

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 DVM, PhD
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Dean Percy From the Departments of Clinical Studies (Rand, Parent) and Pathology (Jacobs, Percy), Ontario Veterinary College, University of Guelph, Guelph, Ontario, NIG 2W1, Canada.

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 DVM, PhD

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SUMMARY

Reference intervals for feline csf cell counts and cytologic variables were determined. Values were derived from 58 adult cats that had normal neurologic examination findings and did not have histologic lesions of the cns. Effect of age or gender was not apparent for any csf variable, and no csf variable was significantly correlated with its corresponding blood value. Total wbc count and neutrophil and eosinophil percentages were positively correlated with the csf rbc count. Thus, proposed reference intervals for feline csf were derived from 33 cats with csf rbc count of < 31 cells/ul. Data for csf samples with range between 31 and 1,700 rbc/μl were also determined. Erythrocyte count was not significantly different in csf collected, using 20- or 22-gauge spinal needles.

SUMMARY

Reference intervals for feline csf cell counts and cytologic variables were determined. Values were derived from 58 adult cats that had normal neurologic examination findings and did not have histologic lesions of the cns. Effect of age or gender was not apparent for any csf variable, and no csf variable was significantly correlated with its corresponding blood value. Total wbc count and neutrophil and eosinophil percentages were positively correlated with the csf rbc count. Thus, proposed reference intervals for feline csf were derived from 33 cats with csf rbc count of < 31 cells/ul. Data for csf samples with range between 31 and 1,700 rbc/μl were also determined. Erythrocyte count was not significantly different in csf collected, using 20- or 22-gauge spinal needles.

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