Evaluation of a commercial staphylococcal bacterin for management of idiopathic recurrent superficial pyoderma in dogs

Douglas J. DeBoer From the Departments of Medical Sciences (DeBoer, Moriello) and Pathobiological Sciences (Thomas, Schultz), School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.

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Karen A. Moriello From the Departments of Medical Sciences (DeBoer, Moriello) and Pathobiological Sciences (Thomas, Schultz), School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.

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Chester B. Thomas From the Departments of Medical Sciences (DeBoer, Moriello) and Pathobiological Sciences (Thomas, Schultz), School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.

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Kevin T. Schultz From the Departments of Medical Sciences (DeBoer, Moriello) and Pathobiological Sciences (Thomas, Schultz), School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.

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SUMMARY

Twenty-one dogs with idiopathic superficial recurrent pyoderma were entered into a double-blind, placebo-controlled study to evaluate the efficacy of a commercial staphylococcal bacterin. The study spanned an 18-week period. All dogs were administered sodium oxacillin orally for the initial 6 weeks of the study. Dogs were given the bacterin or placebo sc, twice weekly at 3- or 4-day intervals, beginning at week 0 and continuing for 18 weeks. Dogs given antibiotics plus the bacterin (n = 13) hada significantly (P < 0.05) better treatment response than those given antibiotic plus placebo.

SUMMARY

Twenty-one dogs with idiopathic superficial recurrent pyoderma were entered into a double-blind, placebo-controlled study to evaluate the efficacy of a commercial staphylococcal bacterin. The study spanned an 18-week period. All dogs were administered sodium oxacillin orally for the initial 6 weeks of the study. Dogs were given the bacterin or placebo sc, twice weekly at 3- or 4-day intervals, beginning at week 0 and continuing for 18 weeks. Dogs given antibiotics plus the bacterin (n = 13) hada significantly (P < 0.05) better treatment response than those given antibiotic plus placebo.

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