Humoral immune response to immediate-early protein of pseudorabies virus in swine with induced or naturally acquired infection

Andrew K. Cheung From the National Animal Disease Center, Agricultural Research Service, USDA, PO Box 70, Ames, IA 50010.

Search for other papers by Andrew K. Cheung in
Current site
Google Scholar
PubMed
Close
 PhD

Click on author name to view affiliation information

SUMMARY

Pseudorabies virus (prv) immediate-early (ie) protein is a nonglycosylated polypeptide localized in the nuclei of infected cells. The ie protein is a regulatory protein that is only synthesized during viral replication and is presented to the immune system of prv-infected swine. Antibodies to the ie protein were demonstrated in swine with induced or naturally acquired infection. However, antiserum raised against purified ie protein could not neutralize prv in vitro.

SUMMARY

Pseudorabies virus (prv) immediate-early (ie) protein is a nonglycosylated polypeptide localized in the nuclei of infected cells. The ie protein is a regulatory protein that is only synthesized during viral replication and is presented to the immune system of prv-infected swine. Antibodies to the ie protein were demonstrated in swine with induced or naturally acquired infection. However, antiserum raised against purified ie protein could not neutralize prv in vitro.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 48 48 19
PDF Downloads 28 28 4
Advertisement