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. Consistent with this, TMPS is currently not subject to special restrictions for veterinary use in food-producing or companion animals and is commonly used in adult horses. However, some equine practitioners are reluctant to use TMPS as a sole treatment in

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in Journal of the American Veterinary Medical Association

fracture, absence of premolar tooth elongation, clinical absence of the left mandibular incisor crown, and the presence of a suspected left mandibular incisor dentinoid (arrowhead [J and K]) are evident. Treatment and Outcome Conservative

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in Journal of the American Veterinary Medical Association

characteristics, the recommendations for treatment of intracranial meningiomas in cats is primarily surgery. However, surgery is not without risks and complications, and occasionally the location and size of the tumor, or patient comorbidities, may preclude

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in Journal of the American Veterinary Medical Association

concentrations have not been established in cats, however, in humans receiving salvage posaconazole therapy for refractory fungal infections, recommended plasma trough concentrations are > l µg/mL. 1 Treatment and Outcome Ocular 1% prednisolone acetate

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in Journal of the American Veterinary Medical Association

diagnostic tool to assess sinus disorders in horses and the use of sinoscopy in both the diagnosis and treatment of these pathologies. Sinusitis in equine patients can be described as primary (dysbacteriosis of the sinus flora) or secondary when a

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in Journal of the American Veterinary Medical Association

eventually crypt cells of the intestinal epithelium. Mortality results from acute immune suppression secondary to lymphocyte depletion, severe gastroenteritis, septicemia, endotoxemia, dehydration, and, ultimately, organ failure. 1 Historically, treatment

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in Journal of the American Veterinary Medical Association

treatment administration. 1 , 4 This inert material has mechanical properties similar to normal synovial fluid 7 and has recently been shown to effectively decrease friction following mechanical and IL-1β biochemical-induced surface damage to cartilage. 8

Open access
in American Journal of Veterinary Research

Abstract

Objective—To evaluate responses of cats with vaccine- associated sarcomas to treatment with surgery and radiotherapy, with or without adjunctive chemotherapy.

Design—Retrospective study.

Animals—76 cats (78 tumors).

Procedure—Medical records were reviewed. Factors potentially associated with survival time, time to recurrence, and time to development of metastases were evaluated.

Results—Following excision, electron beam radiation, and, in some cases, chemotherapy, 32 (41%) cats experienced recurrence, and 9 (12%) cats developed metastases. One- and 2-year survival rates were 86 and 44%, respectively. Median survival time from onset of disease was 730 days (range, 30 to 2,014 days). Median disease-free interval was 405 days (range, 30 to 925 days). Cats that underwent only 1 surgery prior to radiotherapy had a lower recurrence rate than did cats that underwent > 1 surgery and had a significantly longer disease-free interval. Survival time and disease-free interval decreased as time between surgery and the start of radiotherapy increased. Cats that developed metastases had significantly shorter survival times and disease-free intervals than did cats that did not develop metastases. Castrated male cats had a significantly shorter survival time than did spayed female cats. Cats with larger tumors prior to the first surgery had shorter survival times. Twenty-six cats received chemotherapy in addition to surgery and radiotherapy. Whether cats received chemotherapy was not associated with recurrence rate, metastasis rate, or survival time.

Conclusions and Clinical Relevance—Results suggest that excision followed by electron beam irradiation may be beneficial for treatment of cats with vaccine- associated sarcomas. Extent of excision prior to radiotherapy did not seem to be associated with recurrence rate. (J Am Vet Med Assoc 2001;219:1582–1589)

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in Journal of the American Veterinary Medical Association

dogs. Results from a 6-month, phase 3, double-blind, placebo-controlled clinical trial revealed the safety and efficacy of masitinib in the treatment of dogs with nonmetastatic grade 2 or grade 3 cutaneous MCTs. 6 Analysis of data indicated that

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in American Journal of Veterinary Research

consistent with thymoma. Computed tomography was recommended to evaluate surgical resectability, but was declined by the owner. Treatment and Outcome Overnight, the cat was maintained on a continuous rate IV infusion of lactated Ringer solution

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in Journal of the American Veterinary Medical Association