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/dL). Urinalysis was unremarkable. The dog was sedated, and the right carpal joint, right tarsal joint, and left stifle joint were aspirated. On aspiration, the synovial fluid grossly had negligible viscosity and was homogenously dark red and opaque. Three

Open access
in Journal of the American Veterinary Medical Association

Introduction Septic synovitis is an infection of any synovial structure, including joints, tendon sheaths, and bursas, causing inflammation and potentially irreversible damage to the affected structure. 1 Infection within the synovial

Open access
in Journal of the American Veterinary Medical Association

current strategies that involve injecting MSCs or vectors containing anabolic genes or proteins directly into a damaged joint without targeted application. The central goal for the study was to determine whether decellularized synovial scaffolds could be

Full access
in American Journal of Veterinary Research

satisfactory structural scaffold for repair of cartilage defects. 17 Thus, interest has focused on synovial ECM as an alternative to cartilage ECM. The synovium has 2 distinct layers—an intima and subintima, with the intima consisting of a continuous layer of

Full access
in American Journal of Veterinary Research

concentrations increase in serum as well as in synovial fluid after experimental induction of arthritis. 6,7 It has been suggested that SAA is synthesized locally in the inflamed joint in horses, 7 similar to findings reported 8,9 in humans and rabbits. In

Full access
in American Journal of Veterinary Research

and centrifugation elicited an antioxidant effect equivalent to that of the commercial autologous conditioned serum product for stimulated equine synovial fluid cells treated with both blood-derived products. This blood-derived product was named APP. 7

Full access
in American Journal of Veterinary Research

onset of clinical disease. The study reported here focuses on a potential marker for diagnosis and staging of osteoarthritis in synovial fluid. Synovial fluid was chosen for this research as it is known to have sensitive and rapid responses to joint

Full access
in American Journal of Veterinary Research

Septic arthritis is a painful and potentially life-threatening condition in horses that develops when trauma, arthrocentesis, surgery, or bacteremia results in colonization of microorganisms in a joint. 1–5 Bacterial colonization of the synovial

Full access
in American Journal of Veterinary Research

products released from chondrocytes decreased, compared with untreated controls. 11 Stromal cell-derived factor-1 has been measured in synovial fluid and serum in humans and guinea pigs with osteoarthritis, 7,8,11–13 but to our knowledge, has not been

Full access
in American Journal of Veterinary Research

biochemical markers). Synovial fluid concentrations of biomarkers involved in cartilage and synovial membrane metabolism have long been considered as potentially important surrogate measures of the local disease progression. Yet, when attempting to correlate

Full access
in American Journal of Veterinary Research