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. The mesenchymal stromal cells (MSCs) derived from adipose tissue (ASCs) or placenta (PMSCs) belong to the most frequently used proregenerative and immunomodulatory pool in the clinical practice of the stromal cells. Work completed over the past decade

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in Journal of the American Veterinary Medical Association

production of B cells can occur when hematopoietic stem cells are cocultured with BM stromal cells and soluble growth factors. 4–8 These stromal cells provide essential cytokines and other factors that support hematopoiesis and express adhesion molecules

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in American Journal of Veterinary Research
Authors and

thank Dr. Chin-Chi Liu for assistance with the statistical analyses. ABBREVIATIONS ALP Alkaline phosphatase ASC Adipose-derived multipotent stromal cell BSP Bone sialoprotein Ct Cycle threshold DMEM Dulbecco modified Eagle medium DMSO

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in American Journal of Veterinary Research

labeled cells on host tissues in vivo remains to be explored. ABBREVIATIONS FGRE Fast gradient echo GRE Gradient echo MSC Mesenchymal stromal cell SDFT Superficial digital flexor tendon SPIO Superparamagnetic iron oxide a. Cruz

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in American Journal of Veterinary Research

BMSCs from adult mammals. 1–4 Bone marrow stromal cells are ideal for transplantation and spinal cord repair because they can be easily isolated, expanded in culture, and delivered. 1 Bone marrow stromal cells are adherent cells found in cultures of

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in American Journal of Veterinary Research

F eline mesenchymal stem cells (MSCs; sometimes referred to as mesenchymal stromal cells) were first mentioned in the literature in 2002. 1 Significant interest has been placed on the potential of MSC and related animal cell and tissue

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in Journal of the American Veterinary Medical Association

marrow stromal cells have to be cultured over a few weeks from fresh whole bone marrow cells to accumulate sufficient purified cultured BMSCs for transplantation. The important variable, particularly because of decreased proliferation and the propensity

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in American Journal of Veterinary Research

analysis using Microsoft Excel and GraphPad Prism 10. Results Available articles PUBMED search terms included ((feline) AND ((stem cell) OR (stromal cell) OR (stromal vascular fraction))), which resulted in 1,664 articles. A filter was applied

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in Journal of the American Veterinary Medical Association

is exerted on cells when bound to a specific cell membrane receptor. 5 Stromal cell-derived factor-1 α and β (ie, SDF-1) are in the CXC subfamily CXCL12 that binds to the CXCR receptor type 4 and are thought to be housekeeping chemokines. 5 Thus

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in American Journal of Veterinary Research

treatment of SCI. 16 Other cellular treatments are currently being investigated and may hold equal or greater promise. Transplantation of BMSCs improves motor function in rats with acute and chronic paraplegia. 15,19,20,38 Bone marrow stromal cells could

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in American Journal of Veterinary Research