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, gelatin sponge, and poloxamer 407 were previously studied. A favorable pattern of elution was observed for poloxamer 407 gel, with early and sustained release of silver nanoparticles recorded. 11 AgNP variably binds with carrier substrates depending on

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infection management prior to the introduction of antimicrobials in the early 20th century, 6 and microbial resistance against silver is rare. 7 The in vitro antimicrobial effects of silver nanoparticles (AgNPs) against multiple bacteria, viruses, and

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in American Journal of Veterinary Research

materials with in situ generated silver nanoparticles . J Biomed Mater Res B Appl Biomater 2012 ; 100 : 409 – 415 . 23. Politano AD , Campbell KT , Rosenberger LH , et al. Use of silver in the prevention and treatment of infections: silver

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in American Journal of Veterinary Research

. 10.1021/es071301c 22. Rigo C , Ferroni L , Tocco I , Active silver nanoparticles for wound healing . Int J Mol Sci 2013 ; 14 : 4817 – 4840 . 10.3390/ijms14034817 23. Tian J , Wong KKY , Ho C-M , Topical delivery of

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in American Journal of Veterinary Research

KK Ho CM , Topical delivery of silver nanoparticles promotes wound healing . ChemMedChem 2007 ; 2 : 129 – 136 . 22. Morykwas MJ Faler BJ Pearce DJ , Effects of varying levels of subatmospheric pressure on the rate of granulation tissue

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in Journal of the American Veterinary Medical Association

genotoxicity of silver nanoparticles . Biomaterials 2011 ; 32 : 9810 – 9817 . 10.1016/j.biomaterials.2011.08.085 42. Yaman I Durmus AS Ceribasi SM , et al. Effects of Nigella sativa and silver sulfadiazine on burn wound healing in rats . Vet Med

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in American Journal of Veterinary Research

administration of carboplatin in poloxamer 407 after an ulnar osteosarcoma removal in a dog . J Am Anim Hosp Assoc . 2020 ; 56 ( 6 ): 325 – 330 . doi: 10.5326/JAAHA-MS-6926 27. Risselada M , McCain R , Bates MG , et al . Silver nanoparticle elution

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in American Journal of Veterinary Research

use of new gloves and surgical instruments. Future considerations to minimize the risk of implant-associated infection include the use of tissue engineering technology to embed slow-release antimicrobial or silver nanoparticles into the prosthesis. 63

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in Journal of the American Veterinary Medical Association

administered antimicrobials on the basis of both standard microbial culture and molecular diagnostic techniques, the use of selective biocide agents (eg, ionic silver, nanoparticle silver, or cadexomer iodine) and antibiofilm agents (eg, lactoferrin, xylitol

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in Journal of the American Veterinary Medical Association

In a research study 14 in which titanium models were coated with a plasma polymer containing silver nanoparticles, the silver coating showed more than 99.98% reduction in the number of CFUs of biofilm-forming methicillin-resistant S pseudintermedius

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in Journal of the American Veterinary Medical Association