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article summarizes the currently available literature on the use of MSCs and MSC-related products in cats with a focus on study logistics and safety; a second publication summarizes the scope and efficacy. 8 Together, these articles provide guidance for

Open access
in Journal of the American Veterinary Medical Association

protective equipment as methods for controlling the spread of SARS-CoV-2. 2 , 3 Despite these COVID-19 safety protocols, veterinary practices still experienced veterinary team member shortages because of COVID-19 exposures and illnesses, which further

Free access
in Journal of the American Veterinary Medical Association

Summary

Ceftiofur sodium, a broad-spectrum cephalosporin antibiotic, was evaluated for safe use in horses. Male or female horses were allotted to groups and were given either saline solution (control), or 2.2, 6.6, or 11 mg of an aqueous solution of ceftiofur sodium/kg of body weight/d, im, for 30 or 31 days. These dosages are expressed in terms of the ceftiofur free acid, and represent 1 to 5 times the proposed therapeutic dosage (2.2 mg/kg/d) administered for 3 times the maximal recommended duration of 10 days. Some of the horses were euthanatized and necropsied on day 31 or 32. The other horses were evaluated for an additional 30 days, and some were euthanatized and necropsied on day 60. The following types of data were collected: clinical observation; physical examination; pelleted food consumption; body weight; hematologic, serum biochemical, and urinalysis findings; organ weight; gross necropsy observations; and histopathologic findings.

Ceftiofur sodium was generally well tolerated at the exaggerated doses and treatment durations used in these safety studies. Slight to mild decrease in pelleted food consumption was detected in horses given 6.6 or 11 mg of ceftiofur sodium/kg/d. Decreased food consumption began on day 2 and lasted for approximately 9 to 12 days. Generally, mild skeletal muscle irritation was detected by gross and microscopic examination of the injection sites of horses given ceftiofur sodium. Prevalence and severity of the muscle irritation tended to increase with increasing concentration of the dosing solution. Increases in serum aspartate transaminase and creatine kinase activities were detected in some of the ceftiofur-treated horses, and were attributed to mild skeletal muscle irritation at the injection sites. Slight increases in numbers of circulating neutrophils and plasma concentration of fibrinogen were detected in the blood of some ceftiofur-treated horses, and were attributed to mild inflammation at the injection sites or possibly in the large intestine because of a change in bacterial flora.

Free access
in American Journal of Veterinary Research

Abstract

Objective—To identify the perceived market or client demand for dairy on-farm food safety services by veterinarians, the need for a food safety continuing education program, and the educational issues that might be addressed in an on-farm food safety curriculum.

Design—Survey.

Study Population—Consulting dairy veterinarians, government veterinarians located in California, and meat packers slaughtering cull dairy cows in California.

Procedure—Results of a questionnaire supplied to veterinarians and telephone interviews with meat packer representatives were analyzed by use of univariate and multivariate logistic regression procedures.

Results—Some meat packers considered the quality of incoming cull dairy cattle as a control point for food safety hazards. More than 50% of dairy and government- employed veterinarians believed that a current market for on-farm food safety services exists; > 85% believed that a potential market exists. Duration since graduation was negatively correlated with belief in a current market. Government-employed veterinarians were more likely to believe in a current market. Veterinarians were more likely to express a strong interest in offering on-farm food safety services if they believed a current market exists, indicated that they already offer such services, or listed residues and pathogens as the most important issues facing the dairy industry.

Conclusions and Clinical Relevance—Although a potential market for on-farm food safety services is perceived, veterinarians are unsure of their role in this area. New demands of meat packers slaughtering cull dairy cows may be the motivation practitioners need to broach the subject of food safety with clients. (J Am Vet Med Assoc 2000;217:479–484)

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in Journal of the American Veterinary Medical Association

Viewpoint articles represent the opinions of the authors and do not represent AVMA endorsement of such statements. What Is Patient Safety Culture? Veterinary healthcare providers are widely identified as compassionate and trustworthy

Open access
in Journal of the American Veterinary Medical Association

horses in this study subjectively were much more tolerant of infrared temperature measurement at the perineum than rectal temperature measurement, the eye may be preferred if safety near the hind limbs is a concern. The consistent indoor ambient

Free access
in Journal of the American Veterinary Medical Association

avian species were observed to be insensitive to oleander cardioactive glycosides. 23 – 25 This is important because safety studies in rodents appear to have little or no relevance to dogs. Numerous documented cases have demonstrated the potential

Open access
in Journal of the American Veterinary Medical Association
in Journal of the American Veterinary Medical Association

inclusion of quality control samples in prepared matrix. Accuracy of batches analyzed was 94 ± 7.3%, 91.9 ± 4.9%, and 94.2 ± 5.2%. Safety —Evaluation of safety was performed concurrently with the phase II pharmacokinetic study. As described, 5 horses

Full access
in American Journal of Veterinary Research

primary care institutions. Awareness of the effective dose ranges for various medical imaging procedures and the optimal safe use of diagnostic imaging equipment can impact the standard of patient care as well as the safety of personnel working around

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in Journal of the American Veterinary Medical Association