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/distant metastasis; hereafter referred to as cancer recurrence). However, these monitoring tools may not be sensitive enough to detect the presence of residual disease following excisional surgery or early evidence of cancer recurrence following therapeutic

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in American Journal of Veterinary Research

< 0.001) were significant prognostic factors. Treatment efficacy was lower for high stage (large) tumors ( Figure 1 ), tumors with gross postoperative residual disease, and tumors that had been treated previously with other modalities. Histologic type

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in Journal of the American Veterinary Medical Association

residual disease. Oral administration of chemotherapeutics was continued because of the sustained improvement of clinical values and because results of flow cytometry were consistent with residual disease. At 22 months (660 days) after the initial

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in Journal of the American Veterinary Medical Association

. Consultation with the oncology service after 1 month to determine whether radiation therapy could be used to treat the dog's residual disease was advised. Figure 1 Photomicrograph of a section of the liver mass in a 14-year-old Toy Poodle that was removed

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in Journal of the American Veterinary Medical Association

chlorambucil and prednisone over a 1.8-year period decreased the leukocyte and lymphocyte counts to within reference intervals with no adverse effects. Although repeated flow cytometry revealed evidence of residual disease, the fox remained free from clinical

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in Journal of the American Veterinary Medical Association

(6%) had metastasis to an MRLN without concurrent metastasis to an MLN and 10 (21%) had metastasis to both an MRLN and MLN. Among the 16 dogs with metastasis to regional lymph nodes, 13 would have had residual disease if the MRLN had not been removed

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in Journal of the American Veterinary Medical Association

to wide resection of the scar at a site where tumor excision left microscopic residual disease or for which there was insufficient information to confirm complete excision. A review of the medical records of 41 dogs that underwent primary re

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in Journal of the American Veterinary Medical Association

Primary re-excision refers to wide resection of a scar at a site at which initial tumor excision left microscopic residual disease or in which insufficient information was available to confirm completeness of the excision. 1 The goal of primary

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in Journal of the American Veterinary Medical Association

known before surgery), but are generally accepted as 2 to 3 cm laterally and 1 fascial plane deep to minimize the risk of leaving residual disease beyond the grossly visible tumor. 9 , 10 Some authors have proposed that 2-cm lateral margins or a

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in Journal of the American Veterinary Medical Association

examination of the left eye and a bone marrow specimen revealed lymphoma affecting the ciliary body of the left eye and the bone marrow, indicative of stage V disease. As a result of treatment, there was minimal residual disease in the left eye with poor cell

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in Journal of the American Veterinary Medical Association