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limitations are primarily due to the lack of specific feline antibodies, a considerable technological obstacle that the development of functional tests may overcome. In recent years, veterinary regenerative medicine has rapidly expanded as a unique field

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in Journal of the American Veterinary Medical Association

approach in regenerative medicine and tissue engineering. When these concepts were realized in the 1950s, oncologic clinical trials in client-owned dogs with naturally occurring cancer were begun, and such trials are currently at the forefront of

Open access
in American Journal of Veterinary Research

regenerative medicine as they are known to play a foundational role in MSC-associated proregenerative activities. Indeed, exosomes derived from MSCs recapitulate many of the biological activities of MSCs themselves and can even “home” to sites of tissue injury

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in Journal of the American Veterinary Medical Association
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I am delighted to serve as the guest editor for this JAVMA special supplement covering the current state of veterinary regenerative medicine. This special supplement includes an exciting combination of groundbreaking original research as

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in Journal of the American Veterinary Medical Association

. Caplan AI . Adult mesenchymal stem cells for tissue engineering versus regenerative medicine . J Cell Physiol . 2007 ; 213 ( 2 ): 341 – 347 . doi: 10.1002/jcp.21200 4. Viswanathan S , Shi Y , Galipeau J , et al . Mesenchymal stem versus

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in Journal of the American Veterinary Medical Association

(PRP) as a therapeutic agent: platelet biology, growth factors and a review of the literature . In: Lana JF , Andrade Santana MH , Dias Belangero W , et al, eds. Platelet-rich plasma: regenerative medicine: sports medicine, orthopedic and

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in American Journal of Veterinary Research

–26 by several groups. These in vitro studies have raised tremendous interest that MSCs may have the potential to differentiate into functional neural cells and can be used in regenerative medicine to treat patients with neurologic diseases. In line with

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in American Journal of Veterinary Research

Since the 1990s, human embryonic stem cells, induced pluripotent stem cells, and MSCs have emerged as promising tools for regenerative medicine and tissue engineering. 1 Among those, MSCs have several advantages, including safety and the

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in American Journal of Veterinary Research

Introduction Regenerative medicine therapies have become a significant tool for treatment of joint, soft tissue, and a variety of other conditions in animals and humans. Regenerative medicine aims to restore form and function of injured

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in Journal of the American Veterinary Medical Association

. Tramadol, Samsung Pharmaceutical, Seoul, Korea. u. Recombinant human VEGF, R&D systems, Minneapolis, Minn. v. SPSS, version 20, SPSS Inc, Chicago, Ill. References 1. Atala A . Tissue engineering and regenerative medicine: concepts for

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in American Journal of Veterinary Research