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In countries where healthy female dogs (bitches) are not commonly spayed, pyometra has been diagnosed in up to 20% of sexually intact bitches before the age of 10. 1 Clinical signs may include dehydration, anemia, polydipsia, polyuria, anorexia

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in Journal of the American Veterinary Medical Association

adhesions that was obstructive and precluded cervical patency. Pyometra secondary to transluminal cervical adhesions was diagnosed. The purulent material was removed from the uterus over a period of days in an effort to reduce potential contamination

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in Journal of the American Veterinary Medical Association

Pyometra is a common disease of sexually intact female dogs 1 , 2 and has been studied extensively as a model for sepsis and systemic inflammation. 3 – 7 Ovariohysterectomy (OHE) is well established as the recommended treatment for all cases of

Open access
in Journal of the American Veterinary Medical Association

Pyometra, infection of the uterus, can be a life-threatening condition for female cats (queens). 1 Prior research on pyometra has primarily focused on its occurrence in bitches, with few studies documenting the prevalence, characteristics, and

Open access
in Journal of the American Veterinary Medical Association

progesterone, while removing the uterus to prevent pregnancy and uterine disease such as pyometra. Currently, no evidence has been presented in regard to its efficacy in sterilization or development of stump pyometra or other sex hormone–related disorders, and

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in Journal of the American Veterinary Medical Association

range, > 5 to 8 ng/mL) and 30.42 pg/mL (reference range, < 10 pg/mL), respectively. On the basis of these findings, the diagnosis was amended to type II vaginal fold prolapse with pyometra during diestrus. Because the cyst in the right ovary might have

Full access
in Journal of the American Veterinary Medical Association

Pyometra is diagnosed in up to 20% 1 of sexually intact female dogs (bitches) before the age of 10 and in approximately 2% 2 of sexually intact female cats (queens) by the age of 13. Pyometra can be life-threatening and lead to severe

Open access
in Journal of the American Veterinary Medical Association

of the large distended, gas-filled structures were emphysematous pyometra, gastric distension-volvulus (GDV), or severe mechanical ileus. The smaller gas-filled structure was most likely a part of the emphysematous pyometra or mechanical ileus

Restricted access
in Journal of the American Veterinary Medical Association

Abstract

Objective—To determine vasopressin (VP) secretory capacity during osmotic stimulation and the response to desmopressin treatment in dogs with pyometra and control dogs.

Animals—6 dogs with pyometra before and after ovariohysterectomy and 6 control dogs.

Procedure—Urine osmolality (Uosm) was measured during 12 hours. Values measured on the first day defined the basal Uosm pattern. On the second day, dogs were given desmopressin to induce a desmopressin-stimulated Uosm pattern. On day 3, the VP response to osmotic stimulation was examined.

Results—Median Uosm on day 1 was 340 mOsm/kg (range, 104 to 1,273 mOsm/kg) and 807 mOsm/kg (range, 362 to 1,688 mOsm/kg) in dogs with pyometra before and after surgery, respectively, and 1,511 mOsm/kg (range, 830 to 1,674 mOsm/kg) in control dogs. Median Uosm during desmopressin treatment was 431 mOsm/kg (range, 168 to 1,491 mOsm/kg) and 1,051 mOsm/kg (range, 489 to 1,051 mOsm/kg) in dogs with pyometra before and after surgery, respectively, and 1,563 mOsm/kg (range, 1,390 to 2,351) in control dogs. In dogs with pyometra, threshold for VP secretion was lower before surgery (median, 340 mOsm/kg; range, 331 to 366 mOsm/kg) than after surgery (median, 358 mOsm/kg; range, 343 to 439 mOsm/kg) or in control dogs (median, 347 mOsm/kg; range, 334 to 360 mOsm/kg). Highest maximum plasma VP values were found in dogs with pyometra.

Conclusions and Clinical Relevance—Dogs with pyometra had increased urine concentration in response to desmopressin but not to the degree of control dogs, whereas VP secretory ability was not reduced. (Am J Vet Res 2004;65:404–408)

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in American Journal of Veterinary Research

through May 2002, those with a presumptive diagnosis of pyometra for which treatment included ovariohysterectomy were entered in the study after informed owner consent was obtained. The presumptive diagnosis was made on the basis of signalment, history

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in American Journal of Veterinary Research