Search Results
Introduction Pentobarbital is a preferred euthanasia option for animals; however, it presents animal disposal challenges. The Chemical Abstracts Service number for pentobarbital is 57-33-0. The PubChem ID is 23676152, and the molecular formula
T he current AVMA euthanasia guidelines acknowledge the unique challenges inherent to reptile euthanasia. 1 Ideally, intravascular administration of sodium pentobarbital, the primary active ingredient in euthanasia solution, is preferred. 1 , 2
, sodium pentobarbital) per 4.5 kg body weight, as an acceptable method for euthanasia of an unconscious or anesthetized animal. The recommended dose of 3 mL of barbiturate/4.5 kg body weight is anecdotal and experiential, meaning less volume may be enough
Introduction Euthanasia of animals with pentobarbital agents occurs throughout the US, including in companion animals, livestock, research animals, and wildlife. Despite this, there are little data available to evaluate outcomes, including
for acceptable methods of euthanasia in individual reptiles primarily recommend the administration of barbiturates, namely sodium pentobarbital, with the intravascular route preferred. 2 Sodium pentobarbital is the primary active ingredient in many
Summary
Pentobarbital alone, pentobarbital plus 1% lidocaine solution, pentobarbital plus 2% lidocaine solution, and pentobarbital plus 3% lidocaine solution were each used to euthanatize 6 dogs. For each dog, time between the beginning of injection of the euthanasia solution and each of the following events was recorded: collapse, onset of apnea, flat-line electrocardiogram, flat-line electroencephalogram, loss of palpable heartbeat, and loss of palpable pulse. Any signs of pain or discomfort were also recorded.
There were no significant differences among groups except for time to flat-line electrocardiogram. Dogs euthanatized with pentobarbital alone had significantly longer times than did dogs euthanatized with pentobarbital in combination with any of the lidocaine concentrations. We concluded that pentobarbital in combination with lidocaine was a reasonable alternative to pentobarbital alone when euthanatizing dogs.
C urrently, one of the most common methods of equine euthanasia is an overdose of intravenous barbiturates (pentobarbital) either alone or after sedation. However, differences in local regulations of rendering plants and landfills limit options
induced. The study was performed with anesthesia with fentanyl b and pentobarbital, c with no other means of increasing vagal tone. The German Shepherd Dogs were from an established colony with inherited arrhythmias that serve as a model of ventricular
for euthanasia of birds. The IV injection of a euthanasia agent, such as pentobarbital, is currently indicated as an acceptable method. The guidelines state that this is the quickest and most reliable method when it can be performed without causing
Summary
The relative myocardial irritant properties of halothane, isoflurane, and pentobarbital were evaluated in chickens. Sixteen adult male broiler chickens were randomly assigned to 1 of 3 groups: group-1 chickens were anesthetized with pentobarbital (30 mg/kg, iv), group-2 chickens were anesthetized with halothane (end tidal halothane 1.2%), and group-3 chickens were anesthetized with isoflurane (end tidal isoflurane 2.1%). Birds in any 2 of the 3 treatment groups were tested on any 1 day. Local anesthesia was induced, and blood pressure, heart rate, ecg, and blood gas variables were measured before general anesthesia was induced. Positive-pressure ventilation with an inspired O2 fraction > 0.95 was adjusted to result in an end tidal CO2 concentration that reflected a PaCO2 similar to that obtained prior to anesthesia and ventilation. All measurements were repeated. The threshold for ventricular fibrillation in response to electrical stimulation of the heart was then determined for all birds. Effects of anesthesia on hemodynamic and blood gas variables were similar in all 3 groups. Compared with halothane or pentobarbital, isoflurane anesthesia resulted in a significantly (P < 0.05) lower threshold for electrical fibrillation of the heart.
