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calcification was seen. No significant abnormalities were observed in the thorax. The changes were most suggestive of neoplasia, such as intraosseous/intracranial meningioma, lymphoma, osteosarcoma, or fibrosarcoma. Other differential diagnoses included an

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in Journal of the American Veterinary Medical Association

humans, such as in rheumatoid arthritis, during pregnancy, and in metastatic bone carcinoma. 3,14–18 However, this assay has not yet been used to evaluate bone resorption in canine cancer patients. Osteosarcoma is the most common primary bone tumor in

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in American Journal of Veterinary Research

Osteosarcoma is the most common primary bone tumor in dogs and has aggressive behavior. 1 Many negative prognostic factors have been associated with osteosarcoma in dogs, including older age, 2 high serum ALP activity, high serum ALP activity

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in Journal of the American Veterinary Medical Association

Appendicular osteosarcoma is the most common primary bone tumor in dogs. 1 Curative-intent treatment options typically consist of a combination of local disease treatment (amputation, limb-sparing surgery, or stereotactic radiosurgery) and

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in Journal of the American Veterinary Medical Association

Feline primary bone tumors are rare, with an incidence of 4.9/10,000 cases. 1 Osteosarcoma is the most common primary bone tumor in cats, accounting for 70% to 80% of all primary bone tumors. 2 , 3 Although osteosarcoma in cats usually occurs in

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in Journal of the American Veterinary Medical Association

placement of a specialized TPLO bone plate. 5 Since the procedure was introduced, there have been several reports 3,6–9 of sarcomas occurring at the TPLO site, with osteosarcoma being the most commonly reported tumor type. Although development of

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in Journal of the American Veterinary Medical Association

antineoplastic activity of artemisinin in humans with cancer and human cell lines, as well as anecdotal reports of efficacy in dogs with cancer (especially osteosarcoma), an increasing number of pet owners are treating their cancer-affected dogs with artemisinin

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in American Journal of Veterinary Research

Osteosarcoma commonly arises in metaphyseal bone of large- or giant-breed dogs and is the most common primary bone tumor in dogs. 1–5 In previous reports, 1,6 spontaneously occurring osteosarcoma of the tibia accounted for 19 of 128 (14.8%) to

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in Journal of the American Veterinary Medical Association

Although neoplasia of the skeleton occurs in all species, the incidence of osteosarcoma in domestic dogs is much higher than that in humans. 1,2 Skeletal neoplasia is diagnosed in > 8,000 dogs each year, and up to 85% of those dogs have primary

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in American Journal of Veterinary Research

Osteosarcoma is the most common primary bone tumor in dogs, accounting for 85% of all bone cancers. 1 In dogs, it is highly malignant because it is locally aggressive and has a high probability of metastasis. Radiotherapy is a commonly used local

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in American Journal of Veterinary Research