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large animal disease model candidate for inherited peripheral neuropathy. Neurofilament light chain (NfL) concentration can be used as a sign of axonal degeneration and in humans is a promising potential biomarker for a wide host of neurodegenerative

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in American Journal of Veterinary Research

-reactive protein, amyloid-β proteins, phosphorylated τ proteins, neurofilament light chain protein, and glial fibrillary acidic protein. Additional evaluations should include routine ophthalmoscopic exams for hypertensive retinopathy and interstitial fluid

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in American Journal of Veterinary Research

  protein 2 R: GCTTAGCGAGTGCAGCAGTGAC   NEFH Neurofilament heavy chain F: GGAGGTTCCTGCCAAGGTGA Neuron     R: CTCTGCTGCTTTGCTGGGTTC   NEFL Neurofilament light chain F: TGAATATCATGGGCAGAAGTGGAA Neuron     R

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in American Journal of Veterinary Research

, et al . Cerebrospinal fluid lactate in dogs with inflammatory central nervous system disorders . J Vet Intern Med . 2019 ; 33 ( 6 ): 2701 – 2708 . doi: 10.1111/jvim.15606 51. Yun T , Koo Y , Chae Y , et al . Neurofilament light chain as

Open access
in American Journal of Veterinary Research

suspected NME and NLE, and the small number of patients in this study necessitate a cautious interpretation of this finding. Implementing therapeutic biomarker monitoring such as neurofilament light chain with neurologic examination can help evaluate the

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in Journal of the American Veterinary Medical Association