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Shortly after birth, neonatal foals are active, agile, and responsive to the environment; however, they predictably collapse and become flaccid during a particular type of physical restraint. 1–5 This phenomenon, previously referred to by various

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in American Journal of Veterinary Research

moment curve was 1,636,554 ± 931,458 ng([h] 2 /mL), and the terminal half-life was 26.6 ± 11.6 hours. Figure 1— Serum gallium concentration versus time curves for 6 neonatal foals after intragastric administration of GaM (20 mg/kg). Table 1

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in American Journal of Veterinary Research

early goal-directed therapy in critically ill people. 11–14 Shock is commonly encountered in neonatal foals, primarily as a result of sepsis, but therapeutic endpoints in equine medicine are largely reliant on assessment of physical examination

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in American Journal of Veterinary Research

Administration of supplemental oxygen is commonly performed to increase the oxygen content of blood in hypoxemic neonatal foals. 1 In a neonatal foal, oxygen can be provided via a face mask, nasal cannula, or transtracheal catheter or by means of

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in American Journal of Veterinary Research

in neonatal foals with sepsis by means of a low-dose (0.1 μg/kg [0.045 μg/lb]) ACTH stimulation test and a paired low-dose and high-dose (10 μg/foal and 100 μg/foal) ACTH stimulation test. 7,20 Traditionally, to diagnose absolute adrenal gland

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in Journal of the American Veterinary Medical Association

or absence of uveitis as part of the grading criteria 4 ; however, the authors are aware of only 1 published study 7 in the peer-reviewed literature that described the proportion of neonatal foals with uveitis as an ocular manifestation of systemic

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in Journal of the American Veterinary Medical Association

cortisol in response to the stress of severe illness. 26 Although septic neonatal foals with CIRCI may also potentially benefit from hydrocortisone replacement, such treatment has not been critically evaluated in foals. Given the marked differences in HPA

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in American Journal of Veterinary Research

Liver disease in adult horses has been well described, 1–3 but to our knowledge, there is little published information about liver disease in neonatal foals beyond case reports and small case series. 4–8 Reported causes of liver disease in

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in Journal of the American Veterinary Medical Association

Septicemia is a common clinical entity in neonatal foals, and this disease process and its associated complications (eg, septic arthritis) are one of the leading causes of morbidity and death in neonatal foals. 1,2 Although various bacterial

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in Journal of the American Veterinary Medical Association

fluid in the distal portion of the airways or interstitium and dependent atelectasis may complicate the accurate interpretation of images because radiographic findings can appear similar in newborn or recumbent neonatal foals. 13,14 Radiographic

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in American Journal of Veterinary Research