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. Macrophages and multinucleated giant cells within this lesion had numerous intracytoplasmic, gram-positive, Ziehl-Neelsen acid fast-positive, rod-shaped bacilli. The bacteria were also positive to the immunohistochemical (IHC) stain for Mycobacterium spp

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in Journal of the American Veterinary Medical Association

for Mycobacterium bovis , the causative agent of bTB, is important for mitigating the risk of infection for cattle herds. Feed contaminated by infected deer is believed to be 1 mode of transmission for M bovis to cattle. 1 Results of a previous

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in American Journal of Veterinary Research

the presence of acid-fast bacilli in macrophages in all areas of histiocytic inflammation. Mycobacterium simiae complex was cultured from the liver by use of liquid culture media a,b and confirmed via HPLC. b A 5-year-old female Micronesian

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in Journal of the American Veterinary Medical Association

media used for microbial culture. Special stains were used to confirm the colonies were formed by gram-positive acid-fast rod-shaped organisms. The mycobacterium pure isolate was sent to a specialty reference laboratory b for further identification and

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in Journal of the American Veterinary Medical Association

The discovery of the causative agent of bovine tuberculosis ( Mycobacterium bovis ) in a wildlife reservoir (free-ranging white-tailed deer [ Odocoileus virginianus ]) in 1994, and subsequent discovery of infected cattle herds in the northeastern

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in American Journal of Veterinary Research

tissues in experimental studies, 6–8 but vaccinated cattle are not fully protected against infection and can still shed MAP in their feces. Mycobacterium avium subsp paratuberculosis is a facultative intracellular bacterium that is able to survive

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in American Journal of Veterinary Research

potentially involved in phagocytosis. 4–6 Complement receptors (CD11b/ CD18 and CD11c/CD18) are thought to be the major receptors involved in phagocytosis of Mycobacterium tuberculosis and Mycobacterium avium subsp avium organisms. 6 However, other

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in American Journal of Veterinary Research

Bovine tuberculosis is caused by Mycobacterium bovis , which is a zoonotic pathogen. 1 In 1917, the USDA initiated a state-federal-industry eradication program to address bovine tuberculosis in cattle. 2 Consequently, bovine tuberculosis has

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in Journal of the American Veterinary Medical Association

Tuberculosis is an infectious, granulomatous disease caused by bacilli of the genus Mycobacterium that has affected humans since prehistoric times. 1 Tuberculosis caused by Mycobacterium bovis affects a number of mammalian species and was a

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in American Journal of Veterinary Research

Mycobacterium avium subsp paratuberculosis is the etiologic agent of paratuberculosis (also known as Johne's disease), a severe chronic enteritis of ruminants. 1 On entering the oral cavity, MAP organisms target mucosa-associated lymphoid

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in American Journal of Veterinary Research