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History A laboratory fish facility experienced an acute increase in mortality in 1-year-old medaka ( Oryzias latipes ) over a 2-month period. The facility housed approximately 400 medaka in 60 2-L tanks. Up to 10 fish/d were found dead or
induction and recovery times. 23 Similarly, smaller medaka ( Oryzias dancena ) are more sensitive to anesthesia with lidocaine. 24 This could explain why times to apnea were shorter in the present study than in another study conducted on adult goldfish. 10
– 60 . 29. Tchornobay AM Claudy AL Perrot JL , Fatal disseminated Mycobacterium abscessus from Japanese medaka . J Aquat Health 1992 ; 9 : 234 – 238 . 30. Perl A Frelier PF Bercovier H . Red drum Sciaenops ocellatus mortalities
medaka and channel catfish exposed to N -methyl- N '-nitro- N -nitrosoguanidine . Toxicol Pathol 1996 ; 24 : 696 – 706 . 10.1177/019262339602400604
Organ. 2011 ; 96 ( 1 ): 61 – 68 . 21. Torikata C , Mukai M , Kageyama K . Spontaneous olfactory neuroepithelioma in a domestic medaka ( Oryzias latipes ) . Cancer Res. 1989 ; 49 ( 11 ): 2994 – 2998 . 2164606 22. Koike K , Jay G
Zeta Research Award in the Basic Sciences category. The Psi Chapter at North Carolina State University submitted Dr. Hobbie's manuscript “Toward a molecular equivalent dose: Use of the medaka model in comparative risk assessment.” Each award consists
”; Third place: K.R. Hobbie, North Carolina State University and United States Environmental Protection Agency, for “Mechanisms of DMN-induced hepatic neoplasia in the F344 rat versus the medaka fish.” Category of natural disease , First place: R. Sura
