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rebreathing circuit and a ventilator-integrated anesthesia machine (Aestiva 5/7900; GE-Datex Ohmeda). Anesthetic maintenance was isoflurane in oxygen (1 to 2 L/min) targeting the end-tidal concentration of isoflurane (ET ISO ) between 1.4 and 1.6% as

Open access
in American Journal of Veterinary Research

infusion rates of remifentanil during anesthesia with equipotent concentrations of isoflurane in mechanically ventilated dogs and the possible correlation between opioid-induced changes in plasma vasopressin concentrations with some hemodynamic variables

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in American Journal of Veterinary Research

anesthetic dose afforded by opioid receptor agonists is associated with reduced magnitude of cardiovascular depression in some species. 6,7 Fentanyl has been shown to reduce isoflurane MAC in rabbits 8 ; however, to our knowledge, whether this provides

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in American Journal of Veterinary Research

Isoflurane is commonly used for inhalation anesthesia in dogs. Use of isoflurane often results in vasodilation, which can potentially cause hypotension. 1 Administration of premedication agents (tranquilizers, analgesics, and anxiolytics) before

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in American Journal of Veterinary Research

allows comparison of anesthetic agents by potency and the ability to determine the MAC-sparing effects of other classes of drugs. Although isoflurane MAC among species is relatively consistent, deviations as high as 40% have been reported for some

Open access
in American Journal of Veterinary Research

anesthetic induction with diazepam and ketamine or xylazine and ketamine, with subsequent maintenance of anesthesia with isoflurane, in foals undergoing laparotomy and laparoscopy. Materials and Methods Animals —The University of Guelph Animal Care

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in American Journal of Veterinary Research

Awake adult horses maintain an ICP of approximately 2 mm Hg that varies little with head position, 1 which suggests that CBF and CBV are highly regulated in the presence of fluctuating hydrostatic gradients. Isoflurane administration causes

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in American Journal of Veterinary Research

the MAC of isoflurane; for example, MAC reductions as high as 25% can be safely achieved in dogs. 9,10 The clinical use of most NMDA antagonists, however, is hampered by short duration of action, low therapeutic index, and narrow separation between

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in American Journal of Veterinary Research

–7 A low dose of acepromazine (0.05 mg/kg, IV) potentiated isoflurane-induced vasodilation but did not alter CO in dogs, 7 suggesting that the predominant cardiovascular effect of acepromazine is systemic hypotension. Dexmedetomidine is a highly

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in Journal of the American Veterinary Medical Association

Inhalation anesthesia is frequently used in avian patients for examination, diagnostic investigation, and surgical procedures, 1 as well as for research and management purposes. Traditionally, isoflurane has been the agent of choice for avian

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in American Journal of Veterinary Research