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C anine glaucoma constitutes a group of diseases inducing degeneration of the retinal ganglion cells and optic nerve, with elevated intraocular pressure (IOP) being a predominant risk factor. 1 , 2 Regardless of the proposed mechanisms or

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in American Journal of Veterinary Research

without auriculopalpebral nerve block have been comparable. 1,3 The effect of head position on IOP has been well documented for humans. Intraocular pressures are increased by 2 to 4 mm Hg in the supine versus the sitting or standing positions. 17

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in American Journal of Veterinary Research

in dromedary camels. ABBREVIATIONS CI Confidence interval CV Coefficient of variation IOP Intraocular pressure Footnotes a. Alcaine (proparacaine hydrochloride 0.5% ophthalmic solution), Alcon Laboratories Inc, Fort Worth

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in American Journal of Veterinary Research

evaluating the efficacy of glaucoma treatments. Intraocular pressure is determined by aqueous humor volume, choroidal blood volume, vitreous humor volume, scleral rigidity and compliance, extraocular muscle tone, and external pressure applied to the globe. 1

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in American Journal of Veterinary Research

Intraocular pressure is maintained within a specific range by the CNS with a balance between aqueous humor production and outflow. 1,2 The IOP can be affected by 3 principal factors: external pressure, scleral rigidity, and intraocular changes. 2

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in American Journal of Veterinary Research

. Discussion Intraocular pressure is dynamic and fluctuates from minute to minute as the physiologic state changes. Fluctuations in IOP associated with the time of day could affect diagnostic interpretations and therapeutic decisions. 13 Measurements of IOP

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in American Journal of Veterinary Research

wildlife species. 11 Intraocular pressure can be indirectly measured by means of tonometry via indentation, 12,13 applanation, 14–17 or rebound techniques. 18 To our knowledge, IOP has been determined in 4 reptile species: American alligators

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in American Journal of Veterinary Research

regimen and 14.34 ± 2.69 mm Hg for the placebo regimen. Most IOP measurements were within the reference range for dogs (10 to 20 mm Hg). Intraocular pressure was not significantly associated with treatment ( P = 0.46), the interaction between treatment

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in American Journal of Veterinary Research

Intraocular pressure is maintained by the constant production and drainage of aqueous humor. Accurate IOP measurement is part of the diagnosis of glaucoma and uveitis and is critical for monitoring the response to treatment. Prior studies 1,2 in

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in Journal of the American Veterinary Medical Association

. This calcium-channel blocker should also be evaluated for its IOP-decreasing and neuroprotective effects in dogs with glaucoma. 10,17,25 ABBREVIATIONS IOP Intraocular pressure MAP Mean arterial blood pressure a. Wang RF, Gagliuso

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in American Journal of Veterinary Research