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: 9524075 . doi: 10.1155/2018/9524075 13. Deimel LP , Li Z , Ranasinghe C . Interleukin-13 as a target to alleviate severe coronavirus disease 2019 and restore lung homeostasis . J Clin Transl Res . 2021 ; 7 ( 1 ): 116 – 120 . 14. Peng H

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in American Journal of Veterinary Research

-10, or TNF-α expression did not significantly differ with age, but IL-1β and IL-8 expression appeared to increase with age. Interleukin-1 plays an important role in nonspecific immunologic defense, and IL-8 is an important proinflammatory chemokine

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in American Journal of Veterinary Research

10 minutes, and 40 cycles at 95°C for 15 seconds and 60°C for 1 minute. Fluorescence signals were measured at the end of each cycle. All reactions were performed in duplicate. Interleukin-4, IL-5, and IL-13 gene expression were standardized to the

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in American Journal of Veterinary Research

cytokine production. Interleukin-10 is a part of the host protective mechanisms during endotoxemia. 1 In the present study, epinephrine and norepinephrine increased LPS-stimulated production of IL-10, which is similar to that observed in a study 17 with

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in American Journal of Veterinary Research

rates. 6–8 Inflammation associated with transfusion results, in part, from the accumulation of cytokines in stored blood products. 1,2 Interleukin-1β, IL-8, and TNF-α are cytokines that increase in concentration in human whole blood and PRBCs during

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in American Journal of Veterinary Research

CCDC88C Coiled-coil domain containing 88C COMP Cartilage oligomeric matrix protein FZD Frizzled family receptor GDF Growth differentiation factor GSK Glycogen synthase kinase IL Interleukin LRP Lipoprotein receptor-related protein OA

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in American Journal of Veterinary Research

cytokines and growth factors. Interleukin-1, which is a catabolic cytokine, is a potent known mediator of cartilage loss that can lead to osteoarthritis. 6 The cytokine induces a cascade of inflammatory and catabolic events, including the expression of

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in American Journal of Veterinary Research

ADAMTS A disintegrin and metalloproteinase with thrombospondin motifs BC-3 Aggrecan arginine antibody EF1 Elongation factor 1 GAG Glycosaminoglycan IGD Interglobular domain IL Interleukin MMP Matrix metalloproteinase Mt4-MMP Membrane type 4

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in American Journal of Veterinary Research

in many species. Cytokines are expressed in a variety of cells, especially when cells are under stress in situations such as invasion by foreign substances (eg, viruses and bacteria), allergic reactions, and trauma or injury. 1 Interleukin-6 acts as

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in American Journal of Veterinary Research

for the expression of each gene at each concentration of tiludronate evaluated may have prevented an association from being detected. Interleukin-6 has a proinflammatory role in the development of osteoarthritis via modulation of MMP expression. 41

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in American Journal of Veterinary Research